Results 11 to 20 of about 845,922 (255)
Glycan Stability and Flexibility: Thermodynamic and Kinetic Characterization of Nonconventional Hydrogen Bonding in Lewis Antigens. [PDF]
J Am Chem Soc, 2023 We provide evidence for CH-based nonconventional hydrogen bonds (H-bonds) for 10 Lewis antigens and two of their rhamnose analogues. We also characterize the thermodynamics and kinetics of the H-bonds in these molecules and present a plausible ...
Kwon J +9 more
europepmc +3 more sources
H. pylori α1-3/4-fucosyltransferase (Hp3/4FT)-catalyzed one-pot multienzyme (OPME) synthesis of Lewis antigens and human milk fucosides. [PDF]
Chem Commun (Camb), 2017 Lewis antigens and fucosylated human milk oligosaccharides were efficiently produced by an Hp3/4FT-catalyzed OPME fucosylation system.
Yu H +13 more
europepmc +2 more sources
H pylori and Lewis antigens [PDF]
Gut, 2000 See article on page 18 Lipopolysaccharide (LPS) of many Helicobacter pylori strains expresses Lewis antigens (Lex, Ley, Lea, Leb) which are similar to those expressed by gastric epithelial cells (“molecular mimicry”).1 In addition, H pylori LPS displays phase variation in these antigens—that is, the high frequency, reversible switching of phenotype2;
B J, Appelmelk +1 more
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Journal of Applied Hematology, 2020 Leukocyte adhesion deficiency type II (LAD II) is a rare hereditary disorder caused by the mutation in the guanosine diphosphate-fucose transporter gene (SLC35C1).
Khalid Batarfi +4 more
doaj +1 more source
Systematic chemoenzymatic synthesis of O -sulfated sialyl Lewis x antigens [PDF]
, 2016 O-Sulfated sialyl Lewis x antigens play important roles in nature. However, due to their structural complexity, they are not readily accessible by either chemical or enzymatic synthetic processes.
Tasnima, Nova +8 more
core +1 more source
Mycobacterium tuberculosis Infection Up-Regulates Sialyl Lewis X Expression in the Lung Epithelium
Microorganisms, 2021 Glycans display increasingly recognized roles in pathological contexts, however, their impact in the host-pathogen interplay in many infectious diseases remains largely unknown.
Rita Matos +10 more
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Lewis b antigen is a common ligand for genogroup I norovirus strains
FEBS Open Bio, 2022 Noroviruses are major causative agents of nonbacterial acute gastroenteritis in humans. Ten genogroups of noroviruses have been identified to date, among which genogroup I (GI) and genogroup II (GII) noroviruses are major pathogens for humans. GI and GII
Yuichi Someya
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Scientific Reports, 2018 Histo-blood group antigens (HBGAs) and the Lewis and secretor antigens are associated with susceptibility to rotavirus infection in a genotype-dependent manner. Nicaraguan children were prospectively enrolled in two cohorts vaccinated with either RotaTeq
Filemón Bucardo +5 more
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Co-expression of Lewis y antigen with human epididymis protein 4 in ovarian epithelial carcinoma. [PDF]
PLoS ONE, 2013 OBJECTIVE:The main aims of this study were to explore the molecular structural relationship between Human epididymis protein 4 (HE4) and Lewis y antigen by determining their expression patterns and clinical significance in ovarian epithelial carcinoma ...
Huiyu Zhuang +5 more
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Helicobacter pylori, Lewis antigens, and inflammation [PDF]
Gut, 2001 Editor,—In a recent issue of Gut , Zheng et al reported that peptic ulcer disease was associated with increased expression of Lewis (Le) antigens but not cagA , iceA , or vacA in Chinese patients infected with Helicobacter pylori ( (2000) Gut 47:18–22. [OpenUrl][1][Abstract/FREE Full Text][2] ).
M A, Heneghan, A P, Moran
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