Results 31 to 40 of about 845,922 (255)

Fluorescence Melting Curve Analysis for Concurrent Genotyping of Three Tag SNPs in FUT3

Diagnostics, 2022
The synthesis of Lewis blood group antigens is governed by two fucosyltransferase genes, FUT2 and FUT3. Evidence is accumulating to suggest that functional polymorphisms of FUT2 and FUT3 are associated with a variety of clinical conditions.
Mikiko Soejima, Yoshiro Koda
doaj   +1 more source

Fucosylated Antigens in Cancer: An Alliance toward Tumor Progression, Metastasis, and Resistance to Chemotherapy

Frontiers in Oncology, 2018
Aberrant glycosylation of tumor cells is recognized as a universal hallmark of cancer pathogenesis. Overexpression of fucosylated epitopes, such as type I (H1, Lewisa, Lewisb, and sialyl Lewisa) and type II (H2, Lewisx, Lewisy, and sialyl Lewisx) Lewis ...
Athanasios Blanas, Neha M. Sahasrabudhe, Ernesto Rodríguez, Yvette van Kooyk, Sandra J. van Vliet   +4 more
doaj   +1 more source

Transferases reduced in h1299/CD82 cells (Expression levels of possible regulators of sialyl Lewis antigens analysed by DNA microarray).

, 2015
Transferases reduced in h1299/CD82 cells (Expression levels of possible regulators of sialyl Lewis antigens analysed by DNA microarray).
Tsuyoshi Sugiura (732081), Naoya Yoshihama (732073), Koujiro Yamaguchi (732074), Yosuke Kobayashi (732078), Yoshihide Mori (732080), Satomi Chigita (732075), Masakazu Abe (732077), Kotaro Ishii (308438), Naonari Akimoto (732079), Mariko Mine (732076)   +9 more
core   +1 more source

Ecological Impacts of Apiaries [PDF]

, 2021
The Come Clean, Go Green competition is a program dedicated to making Lewis a more sustainable campus with ideas from Lewis Students across all disciplines.
Lewis University
core   +1 more source

Article Molecular analysis of three FUT3 gene single nucleotide polymorphisms and their relationship with the lewis erythrocytary phenotype in a human population of japanese-ancestry living in Tomé Açu, a town in the Brazilian Amazon

Genetics and Molecular Biology, 2007
The Lewis blood group system involves two major antigens, Leª and Le b. Their antigenic determinants are not primary gene products but are synthesized by the transfer of sugar subunits to a precursory chain by a specific enzyme which is the product of ...
Pablo Abdon da Costa Francez, Tereza Cristina de Oliveira Corvelo, Flávio Ricardo Leal da Silva, Sidney Emanuel Batista dos Santos   +3 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Transferases increased in h1299/CD82 cells (Expression levels of possible regulators of sialyl Lewis antigens analysed by DNA microarray).

, 2015
Transferases increased in h1299/CD82 cells (Expression levels of possible regulators of sialyl Lewis antigens analysed by DNA microarray).
Tsuyoshi Sugiura (732081), Naoya Yoshihama (732073), Koujiro Yamaguchi (732074), Yosuke Kobayashi (732078), Yoshihide Mori (732080), Satomi Chigita (732075), Masakazu Abe (732077), Kotaro Ishii (308438), Naonari Akimoto (732079), Mariko Mine (732076)   +9 more
core   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Somatic Evolution of a Germline Antibody Expands its Breadth to Neutralize Early SARS‐CoV‐2 Omicron Variants

Advanced Science, EarlyView.
Engineering of the 148‐germline (148‐GL) antibody reveals a roadmap for overcoming SARS‐CoV‐2 viral escape. By introducing four specific somatic hypermutations, the resulting 148‐M4 variant restores potent neutralization against Omicron BA.1 and BA.4/5.
Huibin Lv, Ziqi Feng, Qi Wen Teo, Chunke Chen, Akshita B. Gopal, Danbi Choi, Timothy J. C. Tan, Yun Sang Tang, Lewis Siu, Armita Nourmohammad, Roberto Bruzzone, Ian A. Wilson, Meng Yuan, Nicholas C. Wu, Chris K. P. Mok   +14 more
wiley   +1 more source

One‐Pot Multienzyme Synthesis of Lewis x and Sialyl Lewis x Antigens [PDF]

Current Protocols in Chemical Biology, 2012
AbstractL‐Fucose has been found abundantly in human milk oligosaccharides, bacterial lipopolysaccharides, glycolipids, and many N‐ and O‐linked glycans produced by mammalian cells. Fucose‐containing carbohydrates have important biological functions. Alterations in the expression of fucosylated oligosaccharides have been observed in several pathological
Hai, Yu, Kam, Lau, Yanhong, Li, Go, Sugiarto, Xi, Chen   +4 more
openaire   +2 more sources