Results 31 to 40 of about 1,731,278 (307)

The Potential Contribution of ABO, Lewis and Secretor Histo-Blood Group Carbohydrates in Infection by Toxoplasma gondii

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
The glycosyltransferases encoded by genes from the human ABO, Lewis, and Secretor histo-blood group systems synthesize part of the carbohydrate antigens in hematopoietic and non-hematopoietic tissues.
Luiz Carlos De Mattos   +5 more
doaj   +1 more source

Expression of Lewisa, Sialyl Lewisa, Lewisx, Sialyl Lewisx, Antigens as Prognostic Factors in Patients with Colorectal Cancer

open access: yesCanadian Journal of Gastroenterology, 2000
BACKGROUND: Altered expression of blood group-related carbohydrate antigens such as sialyl Lewis (Le)x antigen in tumours is associated with tumour progression behaviour and subsequent prognosis.
Tohru Nakagoe   +11 more
doaj   +1 more source

Lewis Antigen Expression byHelicobacter pylori [PDF]

open access: yesThe Journal of Infectious Diseases, 2001
Although Helicobacter pylori express Lewis antigens as a component in the lipopolysaccharide, their role in the infectious process is not well understood. Lewis antigen expression with growth phase was investigated, as well as the distribution of Lewis antigens among isolates from asymptomatic and symptomatic individuals.
D A, Rasko   +3 more
openaire   +2 more sources

Biologic roles of the ABH and Lewis histo‐blood group antigens part II: thrombosis, cardiovascular disease and metabolism

open access: yesVox Sanguinis, 2019
The ABH and Lewis antigens were among the first of the human red blood cell polymorphisms to be identified and, in the case of the former, play a dominant role in transfusion and transplantation.
S. Stowell, C. Stowell
semanticscholar   +1 more source

Helicobacter pylori lipopolysaccharide is synthesized via a novel pathway with an evolutionary connection to protein N-glycosylation. [PDF]

open access: yesPLoS Pathogens, 2010
Lipopolysaccharide (LPS) is a major component on the surface of Gram negative bacteria and is composed of lipid A-core and the O antigen polysaccharide.
Isabelle Hug   +5 more
doaj   +1 more source

Prevalence of Lewis Blood Group Polymorphisms in Southern Thai Blood Donors

open access: yesJournal of Health Science and Medical Research (JHSMR), 2022
Objective: To determine the frequencies of five of the most common (59T>G, 202T>C, 314C>T, 508G>A and 1067T>G) single nucleotide polymorphisms (SNPs) of the FUT3 gene in Thai blood donors and examine their associations with the presence or absence of ...
Natthaphon Nanakorn   +3 more
doaj   +1 more source

Exploring the immunology of parasitism--from surface antigens to the hygiene hypothesis [PDF]

open access: yes, 2009
Helminth immunology is a field which has changed beyond recognition in the past 30 years, transformed not only by new technologies from cDNA cloning to flow cytometry, but also conceptually as our definition of host immune pathways has matured.
R. M. MAIZELS, Maizels, R M
core   +1 more source

Transcriptional Regulation of Fucosyltransferase 1 Gene Expression in Colon Cancer Cells

open access: yesThe Scientific World Journal, 2013
The α1,2-fucosyltransferase I (FUT1) enzyme is important for the biosynthesis of H antigens, Lewis B, and Lewis Y. In this study, we clarified the transcriptional regulation of FUT1 in the DLD-1 colon cancer cell line, which has high expression of Lewis ...
Fumiko Taniuchi   +4 more
doaj   +1 more source

Carbohydrate antigens Lewis a and Lewis b act as tumor markers cooperating with CA19.9 in the management of PDAC patients [PDF]

open access: yes
Background: CA19.9 is the unique marker recommended for the preoperative staging and the follow-up of patients suffering from pancreatic ductal adenocarcinoma (PDAC) but up to 30% of PDAC patients maintain normal CA19.9 values and cannot be monitored in ...
Dei Cas M.   +13 more
core   +3 more sources

Automated glycan assembly of Lewis type I and II oligosaccharide antigens

open access: yes, 2019
Human blood group related glycan antigens are fucosylated (neo-)lactoseries oligosaccharides that playcrucial roles in pathogenic processes. Lewis type-II-chain antigens mark the surface of cancer cells, butare also mediators of bacterial infections.
Guberman, M.   +5 more
core   +1 more source

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