Results 31 to 40 of about 1,731,278 (307)
The glycosyltransferases encoded by genes from the human ABO, Lewis, and Secretor histo-blood group systems synthesize part of the carbohydrate antigens in hematopoietic and non-hematopoietic tissues.
Luiz Carlos De Mattos +5 more
doaj +1 more source
BACKGROUND: Altered expression of blood group-related carbohydrate antigens such as sialyl Lewis (Le)x antigen in tumours is associated with tumour progression behaviour and subsequent prognosis.
Tohru Nakagoe +11 more
doaj +1 more source
Lewis Antigen Expression byHelicobacter pylori [PDF]
Although Helicobacter pylori express Lewis antigens as a component in the lipopolysaccharide, their role in the infectious process is not well understood. Lewis antigen expression with growth phase was investigated, as well as the distribution of Lewis antigens among isolates from asymptomatic and symptomatic individuals.
D A, Rasko +3 more
openaire +2 more sources
The ABH and Lewis antigens were among the first of the human red blood cell polymorphisms to be identified and, in the case of the former, play a dominant role in transfusion and transplantation.
S. Stowell, C. Stowell
semanticscholar +1 more source
Helicobacter pylori lipopolysaccharide is synthesized via a novel pathway with an evolutionary connection to protein N-glycosylation. [PDF]
Lipopolysaccharide (LPS) is a major component on the surface of Gram negative bacteria and is composed of lipid A-core and the O antigen polysaccharide.
Isabelle Hug +5 more
doaj +1 more source
Prevalence of Lewis Blood Group Polymorphisms in Southern Thai Blood Donors
Objective: To determine the frequencies of five of the most common (59T>G, 202T>C, 314C>T, 508G>A and 1067T>G) single nucleotide polymorphisms (SNPs) of the FUT3 gene in Thai blood donors and examine their associations with the presence or absence of ...
Natthaphon Nanakorn +3 more
doaj +1 more source
Exploring the immunology of parasitism--from surface antigens to the hygiene hypothesis [PDF]
Helminth immunology is a field which has changed beyond recognition in the past 30 years, transformed not only by new technologies from cDNA cloning to flow cytometry, but also conceptually as our definition of host immune pathways has matured.
R. M. MAIZELS, Maizels, R M
core +1 more source
Transcriptional Regulation of Fucosyltransferase 1 Gene Expression in Colon Cancer Cells
The α1,2-fucosyltransferase I (FUT1) enzyme is important for the biosynthesis of H antigens, Lewis B, and Lewis Y. In this study, we clarified the transcriptional regulation of FUT1 in the DLD-1 colon cancer cell line, which has high expression of Lewis ...
Fumiko Taniuchi +4 more
doaj +1 more source
Carbohydrate antigens Lewis a and Lewis b act as tumor markers cooperating with CA19.9 in the management of PDAC patients [PDF]
Background: CA19.9 is the unique marker recommended for the preoperative staging and the follow-up of patients suffering from pancreatic ductal adenocarcinoma (PDAC) but up to 30% of PDAC patients maintain normal CA19.9 values and cannot be monitored in ...
Dei Cas M. +13 more
core +3 more sources
Automated glycan assembly of Lewis type I and II oligosaccharide antigens
Human blood group related glycan antigens are fucosylated (neo-)lactoseries oligosaccharides that playcrucial roles in pathogenic processes. Lewis type-II-chain antigens mark the surface of cancer cells, butare also mediators of bacterial infections.
Guberman, M. +5 more
core +1 more source

