Results 91 to 100 of about 8,460,931 (324)

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source

Sex differences for clinical correlates of substantia nigra neuron loss in people with Lewy body pathology

Biology of Sex Differences
Background Lewy body dementia (LBD) phenotype is associated with the presence and degree of Lewy body, Alzheimer’s pathologies, and substantia nigra neuron loss.
Ece Bayram, David G. Coughlin, Ravi Rajmohan, Irene Litvan   +3 more
doaj   +1 more source

Increased weighting on prior knowledge in Lewy body-associated visual hallucinations

Brain Communications, 2019
The mechanisms of visual hallucinations in Lewy body disease are unknown. Zarkali et al. use two-tone stimuli to show that Lewy body hallucinations are associated with altered integration of top-down predictions with sensory evidence.
A. Zarkali, Rick A Adams, S. Psarras, Louise-Ann Leyland, G. Rees, R. Weil   +5 more
semanticscholar   +1 more source

Lewy body progression-associated miRNAs.

, 2014
Ordinal regression analysis was implemented in order to detect miRNAs with monotonic expression patterns across Lewy body stages. Lewy body stages were defined with the Unified Staging System for Lewy Body Disorders as described by Beach et al [46 ...
Charles Adler (559422), Ivana Malenica (559417), Holly Shill (559421), Kasandra Burgos (335934), Raghu Metpally (163684), Marwan Sabbagh (559423), Amanda Courtright (559418), Thomas Beach (559420), Benjamin Rakela (559419), David Craig (117059), Stephen Villa (559424), Waibhav Tembe (117037), Kendall Van Keuren-Jensen (559425)   +12 more
core   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Cognitive and Pathological Influences of Tau Pathology in Lewy Body Disorders

Annals of Neurology, 2018
To use digital histology in a large autopsy cohort of Lewy body disorder (LBD) patients with dementia to test the hypotheses that co‐occurring Alzheimer disease (AD) pathology impacts the anatomic distribution of α‐synuclein (SYN) pathology and that co ...
D. Coughlin, Sharon X. Xie, Mendy Liang, Andrew Williams, Claire S. Peterson, D. Weintraub, C. McMillan, D. Wolk, Rizwan S. Akhtar, H. Hurtig, H. B. Coslett, R. Hamilton, A. Siderowf, J. Duda, K. Rascovsky, Edward B. Lee, V. Lee, M. Grossman, J. Trojanowski, D. Irwin   +19 more
semanticscholar   +1 more source

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen, Mark Paine, Soohyun Lee, Amir Fazlollahi, Baibin (Ben) Wang, John D. O'Sullivan, Peter J. Nestor   +6 more
wiley   +1 more source

A Consistent Reference Service for the Interoperation of EPrint Repositories

, 2006
Current Institutional Repository packages do a poor job of maintaining the article’s metadata in a consistent fashion. Documents and other entities are unreliably identified and there exists no mechanism for correlating related data between multiple ...
Lewy, Timothy
core   +1 more source

Stephan Lewy

, 1995
Stephan Lewy, born March 11, 1925, in Berlin, Germany, provides Holocaust survivor testimony. Interviewer: Ann Solov Walker. Notetaker: Betty Ann Fishman.
Lewy, Stephen, Lewy, Stephan
core   +1 more source

Parkinson’s Disease and Dementia with Lewy Bodies: One and the Same

Journal of Parkinson’s Disease
The question whether Parkinson’s disease dementia (PDD) and dementia with Lewy bodies (DLB) are expressions of the same underlying disease has been vigorously debated for decades.
Per Borghammer, Niels Okkels, Daniel Weintraub   +2 more
doaj   +1 more source