Results 221 to 230 of about 8,460,931 (324)

Regional Overlap of Pathologies in Lewy Body Disorders

Journal of Neuropathology and Experimental Neurology, 2017
Martí Colom‐Cadena, O. Grau-Rivera, L. Planellas, Catalina Cerquera, E. Morenas, Sergio Helgueta, L. Muñoz, J. Kulisevsky, M. Marti, E. Tolosa, J. Clarimón, A. Lleó, E. Gelpí   +12 more
semanticscholar   +1 more source

Clinical heterogeneity of Pisa syndrome across Lewy body disorders: a multicenter comparison of Parkinson's disease and dementia with Lewy bodies. [PDF]

Front Aging Neurosci
Su Z, Liu M, Kuai J, Bao X, Guo X, Zuo M, Wu H, Gan J, Liu S, Ji Y.   +9 more
europepmc   +1 more source

Diagnosing Dementias: Many Names, Many Faces

Journal of the American Geriatrics Society, EarlyView.
Michael Tran Duong
wiley   +1 more source

Design, Synthesis and Molecular Docking Studies of Some Novel Hydrazone Derivatives Based on Trimetazidine as Selective and Potent AChE Inhibitors

Drug Development Research, Volume 87, Issue 7, November 2026.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disease, and cholinergic dysfunction is considered one of the fundamental pathological factors of this disease. Guided by the clinically used acetylcholinesterase (AChE) inhibitor donepezil, we explored trimetazidine dihydrochloride as an accessible starting scaffold to generate ...
Muhammed Oğuzhan Doğan, Begüm Nurpelin Sağlık Özkan, Abdullah Burak Karaduman, Sevgi Karakuş, Yusuf Özkay, Zafer Asım Kaplancıklı, Fatih Tok   +6 more
wiley   +1 more source

The utility of a composite endpoint for tracking disease progression in Lewy body dementia. [PDF]

Alzheimers Dement (N Y)
Matar E, White SR, Taylor JP, Thomas A, McKeith I, Kane J, Lewis S, Surendranathan A, O'Brien J.   +8 more
europepmc   +1 more source

Perivascular Spaces as Determinants of Amyloid, Tau, and Vascular Biomarker Progression

Annals of Neurology, Volume 100, Issue 4, Page 695-708, October 2026.
Objective Magnetic resonance imaging (MRI)‐visible enlarged perivascular spaces (PVS) are markers of cerebral small vessel disease (SVD) and aging, processes implicated in both neurodegenerative and cerebrovascular pathologies. However, longitudinal positron emission tomography (PET) studies examining PVS as a mechanism underlying Alzheimer's disease ...
Audrey Low, Jeffrey L. Gunter, Mingzhao Hu, Sheelakumari Raghavan, Scott A. Przybelski, Christopher G. Schwarz, Kejal Kantarci, Val J. Lowe, Ronald C. Petersen, Jonathan Graff‐Radford, Clifford R. Jack Jr, Prashanthi Vemuri   +11 more
wiley   +1 more source

Exposure to Air Pollutants and Lewy Body and Parkinson Disease-Related Dementias.

JAMA Netw Open
Davydow DS, Pontone GM, Okun MS, Armstrong MJ, Böttger TW, Geels C, Frohn LM, Brandt J, Dreier JW, Christensen J, Pedersen CB, Horsdal HT.   +11 more
europepmc   +1 more source

Spatially resolved molecular signatures of Lewy body dementia. [PDF]

Acta Neuropathol
Jin Y, Chen K, Wixom AQ, Li Z, Koga S, Sekiya H, Xhafkollari G, Castanedes-Casey M, Santhakumar H, Meneses AD, Neff AJ, Bu G, Heckman MG, Liu Y, Ross OA, Dickson DW, Zhao N.   +16 more
europepmc   +1 more source

Elevated endogenous glucagon‐like peptide‐1 as a novel Alzheimer's disease biomarker associated with neuroinflammation and Aβ pathology

General Psychiatry, Volume 39, Issue 5, October 2026.
ABSTRACT Background Alzheimer's disease (AD), a neurodegenerative disorder, is pathologically defined by the accumulation of amyloid‐β (Aβ) plaques, hyperphosphorylated tau tangles and sustained neuroinflammation. Glucagon‐like peptide‐1 (GLP‐1), originally characterised as an incretin hormone, is also expressed endogenously in the brain.
Jianping Li, Chenhui Ji, Jintao Wang, Jinwen Xiao, Haixia Li, Xinyi Xie, Nan Zhi, Yaying Song, Wenwei Cao, Liling Wang, Jieli Geng, Rujing Ren, Gang Wang   +12 more
wiley   +1 more source

Progression to Dementia in Very Late-Onset Schizophrenia-Like Psychosis Stratified by Alzheimer's Disease and Lewy Body Disease Biomarkers: A Retrospective Cohort Study. [PDF]

Psychogeriatrics
Satake Y, Kanemoto H, Taomoto D, Takeda K, Katakami S, Kobayashi M, Matsunaga K, Isohashi K, Suehiro T, Yoshiyama K, Ikeda M.   +10 more
europepmc   +1 more source