Results 241 to 250 of about 8,460,931 (324)

DJ-1 linked parkinsonism (PARK7) is associated with Lewy body pathology.

open access: yesBrain : a journal of neurology, 2016
R. Taipa   +6 more
semanticscholar   +1 more source

Involving People With Dementia in Research: Contributions, Barriers and Evaluation From a Meta‐Synthesis and Qualitative Interview Study

open access: yesHealth Expectations, Volume 29, Issue 5, October 2026.
ABSTRACT Background Patient and Public Involvement and Engagement (PPIE) can enhance the relevance, acceptability and quality of research; however, its meaningful implementation in dementia research remains insufficiently understood. Aim (1) To identify methodological procedures for involving people with dementia (PwD) across the research lifecycle ...
Jörg Meisser   +2 more
wiley   +1 more source

Deep learning-based MRI analysis reveals Lewy body co-pathology accelerates brain aging in Alzheimer's disease. [PDF]

open access: yesAlzheimers Dement
Ahmadi B   +6 more
europepmc   +1 more source

Interventions to Reduce Loneliness in Informal Caregivers of People With Dementia: A Systematic Review

open access: yesJournal of Clinical Nursing, Volume 35, Issue 10, Page 4124-4136, October 2026.
ABSTRACT Aim To summarize the current evidence on reducing loneliness among informal caregivers of people with dementia, such as family members or friends. Design A systematic review. Methods The methodological quality was evaluated using the revised Cochrane risk‐of‐bias tool for randomized controlled trials and the revised JBI critical appraisal ...
Tianxue Hou   +5 more
wiley   +1 more source

Clean, Pleasant, Governed: A Critical Discourse Analysis of Bathing Without a Battle

open access: yesNursing Inquiry, Volume 33, Issue 4, October 2026.
ABSTRACT Bathing Without a Battle is a widely circulated video training resource in residential dementia care, but the assumptions it advances about bathing, refusal, and appropriate nursing practice have received limited critical attention. This paper analyzes how the text constructs resistance to assisted bathing and how it frames legitimate nursing ...
Patricia Morris   +3 more
wiley   +1 more source

SIRT1 in Neurodegenerative Diseases: Molecular Mechanisms, Disease Relevance, and Therapeutic Potential

open access: yesThe FASEB Journal, Volume 40, Issue 17, 15 September 2026.
SIRT1, an NAD+‐dependent deacetylase, supports cognitive resilience by coordinating neuroprotection, synaptic plasticity, autophagy–lysosomal proteostasis, and mitochondrial energy homeostasis. Reduced or dysregulated SIRT1 is associated with protein aggregation, neuroinflammation, mitochondrial dysfunction, synaptic loss, and cognitive decline in ...
Jiabin Duan   +6 more
wiley   +1 more source

Modeling Parkinson's pathology in human iPSC dopaminergic neurons uncovers key mechanisms of Lewy body formation and heterogeneity. [PDF]

open access: yesSci Adv
Mahul-Mellier AL   +16 more
europepmc   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, Volume 13, Issue 9, Page 1791-1806, September 2026.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi   +19 more
wiley   +1 more source

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