Results 241 to 250 of about 8,460,931 (324)
DJ-1 linked parkinsonism (PARK7) is associated with Lewy body pathology.
R. Taipa +6 more
semanticscholar +1 more source
ABSTRACT Background Patient and Public Involvement and Engagement (PPIE) can enhance the relevance, acceptability and quality of research; however, its meaningful implementation in dementia research remains insufficiently understood. Aim (1) To identify methodological procedures for involving people with dementia (PwD) across the research lifecycle ...
Jörg Meisser +2 more
wiley +1 more source
Deep learning-based MRI analysis reveals Lewy body co-pathology accelerates brain aging in Alzheimer's disease. [PDF]
Ahmadi B +6 more
europepmc +1 more source
ABSTRACT Aim To summarize the current evidence on reducing loneliness among informal caregivers of people with dementia, such as family members or friends. Design A systematic review. Methods The methodological quality was evaluated using the revised Cochrane risk‐of‐bias tool for randomized controlled trials and the revised JBI critical appraisal ...
Tianxue Hou +5 more
wiley +1 more source
Preclinical Catecholaminergic Biomarkers of Central Lewy Body Diseases. [PDF]
Goldstein DS.
europepmc +1 more source
Clean, Pleasant, Governed: A Critical Discourse Analysis of Bathing Without a Battle
ABSTRACT Bathing Without a Battle is a widely circulated video training resource in residential dementia care, but the assumptions it advances about bathing, refusal, and appropriate nursing practice have received limited critical attention. This paper analyzes how the text constructs resistance to assisted bathing and how it frames legitimate nursing ...
Patricia Morris +3 more
wiley +1 more source
Cross-sectional analysis of variation in diagnosis of Lewy body dementia in three English regions: data from the DETERMIND programme. [PDF]
Hamilton CA +5 more
europepmc +1 more source
SIRT1, an NAD+‐dependent deacetylase, supports cognitive resilience by coordinating neuroprotection, synaptic plasticity, autophagy–lysosomal proteostasis, and mitochondrial energy homeostasis. Reduced or dysregulated SIRT1 is associated with protein aggregation, neuroinflammation, mitochondrial dysfunction, synaptic loss, and cognitive decline in ...
Jiabin Duan +6 more
wiley +1 more source
Modeling Parkinson's pathology in human iPSC dopaminergic neurons uncovers key mechanisms of Lewy body formation and heterogeneity. [PDF]
Mahul-Mellier AL +16 more
europepmc +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source

