Results 181 to 190 of about 56,147 (276)

Identification of expanded and interrupted ATXN2 repeat expansions in Parkinson's disease and Lewy Body Dementia cohorts. [PDF]

NPJ Parkinsons Dis
Wang L, Milton M, Fearnley LG, Bhalala OG, Bahlo M, Rafehi H.   +5 more
europepmc   +1 more source

Association between Human Leukocyte Antigen Alleles and Neuropathological Outcomes in Lewy Body Disease

Annals of Neurology, Volume 99, Issue 2, Page 492-501, February 2026.
Objective Lewy body disease (LBD) is a complex neurodegenerative disorder characterized by the accumulation of misfolded α‐synuclein in the brain. Neuroinflammation has long been implicated in LBD pathogenesis, and recent genetic studies in Parkinson's disease (a clinical manifestation of LBD) have shown consistent association with the human leukocyte ...
Marios Gavrielatos, Michael G. Heckman, Alexandra I. Soto‐Beasley, Sophia G. Blumenfeld, Xu Hou, Shunsuke Koga, Melissa E. Murray, Koji Kasanuki, Daisuke Ono, Fabienne C. Fiesel, Ryan J. Uitti, Julie A. Fields, Hugo Botha, Vijay K. Ramanan, Kejal Kantarci, Val J. Lowe, Clifford R. Jack, Nilufer Ertekin‐Taner, J. Raphael Gibbs, Bryan J. Traynor, Clifton L. Dalgard, Rodolfo Savica, Jonathan Graff‐Radford, Ronald C. Petersen, R. Ross Reichard, Neill R. Graff‐Radford, Tanis J. Ferman, Bradley F. Boeve, Zbigniew K. Wszolek, Wolfdieter Springer, Ziv Gan‐Or, Emmanuel Mignot, Sonja W. Scholz, Dennis W. Dickson, Owen A. Ross   +34 more
wiley   +1 more source

Donepezil Research in Cognitive Impairment: A Bibliometric and Scientometric Analysis of Global Trends and Pharmacological Perspectives

Brain and Behavior, Volume 16, Issue 2, February 2026.
Donepezil research in cognitive impairment: a bibliometric and scientometric analysis. ABSTRACT Background Cognitive impairment (CI) greatly affects global health and quality of life. Donepezil, a widely used treatment for CI, particularly in Alzheimer's disease, has been extensively studied; however, a comprehensive bibliometric analysis summarizing ...
Wencai Wang, Yinuo Chen, Zijie Xiong, Zun Wang, Wei Ye, Xianfeng Li   +5 more
wiley   +1 more source

Towards optimizing the diagnosis of Lewy body dementia: Lessons from the NACC. [PDF]

Alzheimers Dement
Goodheart AE, Brazier TL, Ye R, Stancu P, Gomperts SN.   +4 more
europepmc   +1 more source

The relevance of cerebrospinal fluid α-synuclein levels to sporadic and familial Alzheimer’s disease [PDF]

, 2018
Bateman, Randall J, Benzinger, Tammie L.S., et al,, Fagan, Anne, Karch, Celeste M, Morris, John C   +5 more
core   +1 more source

Ginsenoside Rg1 as a Multifunctional Therapeutic Agent: Pharmacological Properties, Molecular Mechanisms and Clinical Perspectives in Complementary Medicine

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Ginsenoside Rg1 (Rg1) from Panax ginseng shows multifunctional health effects. Although oral bioavailability is low and blood–brain barrier (BBB) penetration is limited, delivery systems such as liposomes and nanoparticles may improve exposure. Rg1 reduces inflammation/oxidative stress by inhibiting nuclear factor‐κB (NF‐κB) signaling and reactive ...
Hernán Cortés, Enrique Lima, Lorena Duarte‐Peña, Sheila I. Peña‐Corona, Zainab M. Almarhoon, Rajesh Kaverikana, Shivaprasad Shetty Mangalpady, Vinayaka Babu Shet, Nikshitha Manjeshwar, Javad Sharifi‐Rad, Jen‐Tsung Chen, Gerardo Leyva‐Gómez, William N. Setzer, Daniela Calina   +13 more
wiley   +1 more source

Sex and gender differences in Lewy body dementia: a narrative review. [PDF]

Equity Neurosci
Bayram E.
europepmc   +1 more source

Social Cognition in Community Dwelling Persons With Dementia; Is Facial Emotion Recognition Related to Proxy Rated Empathy and Aggression?

International Journal of Geriatric Psychiatry, Volume 41, Issue 2, February 2026.
ABSTRACT Objectives Aggressive behaviour and decreased empathy occur in many dementia syndromes. This may be related to lowered overall cognitive functioning which is a common feature of dementia. However, to date, the role of social cognitive impairments such as facial emotion recognition (FER) deficits in dementias other than behavioural variant ...
Aafra T. Ter Horst, Marleen J. J. Gerritsen, Jacoba M. Spikman   +2 more
wiley   +1 more source

Heat shock protein 10 as a chaperone modulating α‐synuclein amyloid fibril formation

Protein Science, Volume 35, Issue 2, February 2026.
Abstract HSP10 is a well‐known human co‐chaperone that interacts with HSP60 to comprise the HSP60/10 chaperonin complex which upholds mitochondrial proteostasis. HSP10 also demonstrates independent roles in binding to misfolded proteins and interacts with several amyloidogenic client proteins.
Johan N. K. Larsson, Ranjeet Kumar, Fiamma Ayelen Buratti, Sofie Nyström, Pernilla Wittung‐Stafshede, Per Hammarström   +5 more
wiley   +1 more source

α-Synuclein seed amplification assay in Lewy body dementia versus Alzheimer's disease. [PDF]

Alzheimers Dement (Amst)
McWilliam OH, Bsoul R, Lund EL, Waldemar G, Hasselbalch SG, Simonsen AH, Bruun M, von Buchwald C, Aanæs K, Pedersen CK, Andersen ISB, Bech M, Areškevičiūtė A, Frederiksen KS.   +13 more
europepmc   +1 more source