Pregnancy and Live Birth In Women With Pathogenic LHCGR Variants Using Their Own Oocytes [PDF]
The Journal of Clinical Endocrinology & Metabolism, 2019 Abstract Context The LH/chorionic gonadotropin receptor (LHCGR) is mainly expressed in gonads and plays important roles in estradiol production, ovulation, and luteal formation. Women with pathogenic LHCGR variants suffer from infertility, and successful fertility treatments for such women have never ...
Xuefeng Lu +16 more
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Expression profiles of the glucose-dependent insulinotropic peptide receptor and LHCGR in sporadic adrenocortical tumors [PDF]
Journal of Endocrinology, 2008 Glucose-dependent insulinotropic peptide receptor (GIPR) and LHCGR are G-protein-coupled receptors with a wide tissue expression pattern. Aberrant expression of these receptors has rarely been demonstrated in adult sporadic adrenocortical tumors with a lack of data on pediatric tumors. We quantified the GIPR and LHCGR expression in a large cohort of 55
Márcia Helena Soares Costa +13 more
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Letrozole protects against cadmium-induced inhibition of spermatogenesis via LHCGR and Hsd3b6 to activate testosterone synthesis in mice [PDF]
, 2022 Yao Yao +7 more
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A genomic atlas of human adrenal and gonad development [version 1; referees: awaiting peer review] [PDF]
, 2017 Background: In humans, the adrenal glands and gonads undergo distinct biological events between 6-10 weeks post conception (wpc), such as testis determination, the onset of steroidogenesis and primordial germ cell development.
Achermann, JC +9 more
core
Cross-platform gene expression signature of human spermatogenic failure reveals inflammatory-like response [PDF]
, 2017 BACKGROUND The molecular basis of human testicular dysfunction is largely unknown. Global gene expression profiling of testicular biopsies might reveal an expression signature of spermatogenic failure in azoospermic men.
Cappallo-Obermann, Heike +6 more
core
Comparison of real-time quantitative Polymerase Chain Reaction (PCR) and digital droplet PCR for quantification of hormone membrane receptor FSHR, GPER and LHCGR transcripts in human primary granulosa lutein cells [PDF]
, 2020 Samantha Sperduti +5 more
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Novel genes involved in pathophysiology of gonadotropin-dependent adrenal tumors in mice [PDF]
, 2017 Belling, Kirstine González-Izarzugaza +9 more
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Elevated IL-8/TNF-α in follicle fluid of infertile women with endometriosis decrease LHCGR expression in cumulus cells [PDF]
, 2023 Yaoxue Yin +11 more
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