Results 1 to 10 of about 11,867 (232)

Genotyping of cows by LHCGR, FSHR loci and determination of the level of ovulation depending on the expression of the studied genes

Open Veterinary Journal, 2023
Background: Genotyping offers a promising avenue for identifying the healthy reproductive system in cows. The healthy reproductive system in cows is determined by measuring the level of ovulation and by identifying the type polymorphism of specific ...
Yktiyar Sarybayev, Yessengali Ussenbekov, Orynbassar Turebekov, Bekbolat Bekbolat, Ibragim Tutkyshbay   +4 more
doaj   +5 more sources

Downregulation of LHCGR Attenuates COX-2 Expression and Induces Luteinized Unruptured Follicle Syndrome in Endometriosis [PDF]

Frontiers in Endocrinology, 2022
An association between endometriosis and luteinized unruptured follicle syndrome (LUFs) has long been identified. Although inactivating mutation of luteinizing hormone/choriogonadotropin receptor (LHGCR) results in LUFs, whether LHCGR contributes to ...
Ting Geng, Ting Geng, Ting Geng, Yifan Sun, Yifan Sun, Yifan Sun, Lin Cheng, Lin Cheng, Lin Cheng, Yuming Cao, Yuming Cao, Yuming Cao, Ming Zhang, Ming Zhang, Zhidan Hong, Zhidan Hong, Ling Ma, Ling Ma, Yuanzhen Zhang, Yuanzhen Zhang, Yuanzhen Zhang   +20 more
doaj   +4 more sources

LHCGR inactivating variants: single center experience and systematic review of phenotype-genotype of 46,XY and 46,XX patients [PDF]

Endocrine Connections
Background: The data on Leydig cell hypoplasia (LCH) resulting from biallelic Luteinizing hormone/chorionic gonadotropin receptor (LHCGR) inactivating variants is limited to case series.
Rohit Barnabas, Swati Jadhav, Anurag Ranjan Lila, Sirisha Kusuma Boddu, Saba Samad Memon, Sneha Arya, Samiksha Chandrashekhar Hegishte, Manjiri Karlekar, Virendra A Patil, Vijaya Sarathi, Nalini S Shah, Tushar Bandgar   +11 more
doaj   +3 more sources

Significance of FSHR and LHCGR gene polymorphisms on clinical outcomes in gonadotropin-releasing hormone antagonist protocol with freeze-all strategy: A case-control study [PDF]

International Journal of Reproductive BioMedicine
Background: Follicle-stimulating hormone receptor (FSHR) and luteinizing hormone/choriogonadotropin receptor (LHCGR) are integral to ovarian function, facilitating follicle development and maturation through their respective hormonal interactions.
Jayesh Amin, Naga Sandhya Alle, Ami Patel, Bansi Prajapathi, Paresh Makwana, Jaya Prakash, Kota Murali Krishna   +6 more
doaj   +3 more sources

Genetic models for the study of luteinizing hormone receptor function [PDF]

Frontiers in Endocrinology, 2015
The luteinizing hormone/chorionic gonadotropin receptor, LHCGR, is essential for fertility in men and women. LHCGR binds luteinizing hormone (LH) as well as the highly homologous chorionic gonadotropin (CG).
Prema eNarayan
doaj   +4 more sources

Post-trigger luteinizing hormone concentration to positively predict oocyte yield in the antagonist protocol and its association with genetic variants of LHCGR [PDF]

Journal of Ovarian Research, 2023
Background The concentration of human chorionic gonadotropin (hCG)/ luteinizing hormone (LH) after triggering is generally accepted as a predictor of the normal ovarian response to the trigger, but few studies have explored the distribution model of ...
Hao Jin, Haiyan Yang, Jiujia Zheng, Jiechun Zhou, Rong Yu   +4 more
doaj   +2 more sources

Genetic variants (Lhcgr W495X/+) and environmental toxicants (DEHP) synergistically induce DSD by interfering with steroidogenic gene expression [PDF]

Biology of Sex Differences
Background Emerging evidence suggests that genetic variants and environmental toxicants may synergistically contribute to DSD. To test this hypothesis, we employed Lhcgr W495X/+ (luteinizing hormone/chorionic gonadotropin receptor) male mice subjected to
Xie Qigen, Xia Kai, Cao Haiming, Xu Zhe, Gao Yong, Deng Chunhua   +5 more
doaj   +2 more sources

Análise da expressão dos receptores do peptídeo insulinotrópico dependente de glicose (GIPR) e do hormônio luteinizante (LHCGR) nas hiperplasias adrenocorticais humanas [PDF]

, 2009
OBJECTIVE: To analyze the aberrant expression of the GIPR and LHCGR in different forms of adrenocortical hyperplasia: ACTH-independent macronodular adrenal hyperplasia (AIMAH), primary pigmented nodular adrenocortical disease (PPNAD) and diffuse adrenal ...
COSTA, Marcia Helena Soares, DOMENICE, Sorahia, FRAGOSO, Maria Candida Barisson Villares, LATRONICO, Ana Claudia, LUCON, Antonio Marmo, MARTIN, Regina Matsunaga, MENDONCA, Berenice Bilharinho, NISHI, Mirian Yumie   +7 more
core   +3 more sources

A link between high serum levels of human chorionic gonadotrophin and chorionic expression of its mature functional receptor (LHCGR) in Down's syndrome pregnancies [PDF]

Reproductive Biology and Endocrinology, 2005
Human chorionic gonadotrophin (hCG) is released from placental trophoblasts and is involved in establishing pregnancy by maintaining progesterone secretion from the corpus luteum. Serum hCG is detected in the maternal circulation within the first 2–3 wks
Spencer Kevin, Loosfelt Hugues, Papageorghiou Aris, Chambers Anne E, Smallwood Alan, Banerjee Subhasis, Campbell Stuart, Nicolaides Kypros   +7 more
doaj   +2 more sources

Differences in signal activation by LH and hCG are mediated by the LH/CG receptor`s extracellular hinge region [PDF]

Frontiers in Endocrinology, 2015
The human lutropin/choriogonadotropin receptor (LHCGR) can be activated by binding two slightly different gonadotropic glycoprotein hormones, choriogonadotropin (CG) - secreted by the placenta, and lutropin (LH) - produced by the pituitary.
Paul eGrzesik, Annika eKreuchwig, Claudia eRutz, Jens eFurkert, Burkhard eWiesner, Ralf eSchülein, Gunnar eKleinau, Joerg eGromoll, Gerd eKrause   +8 more
doaj   +4 more sources