Results 21 to 30 of about 12,270 (235)
JCRPE, 2019 The LHCGR gene encodes a G-protein coupled receptor that plays a pivotal role in sexual differentiation in males, ovarian development in females and in fertility via its interaction with luteinizing hormone and chorionic gonadotropin.
Mei Yan +5 more
doaj +2 more sources
Differences in signal activation by LH and hCG are mediated by the LH/CG receptor`s extracellular hinge region [PDF]
Frontiers in Endocrinology, 2015 The human lutropin/choriogonadotropin receptor (LHCGR) can be activated by binding two slightly different gonadotropic glycoprotein hormones, choriogonadotropin (CG) - secreted by the placenta, and lutropin (LH) - produced by the pituitary.
Paul eGrzesik +8 more
doaj +4 more sources
Circulating LH/hCG receptor (LHCGR) may identify pre-treatment IVF patients at risk of OHSS and poor implantation [PDF]
Reproductive Biology and Endocrinology, 2011 Background Successful pregnancy via in vitro fertilization (IVF) depends on the recovery of an adequate number of healthy oocytes and on blastocyst implantation following uterine transfer. Two hormones, LH and hCG, utilize a common LH/hCG receptor (LHCGR)
Chambers Anne E +4 more
doaj +2 more sources
Frontiers in Endocrinology, 2021 Infertility is a major concern for couples wanting to have progeny. Despite recent advances in the field of IVF, success rates still need improvement. Understanding the patient’s variability and addressing it with personalized interventions may improve ...
Ramaraju GA +9 more
doaj +2 more sources
Prevalence and genetic etiology of poly-cystic ovarian syndrome (PCOS) in Mauritania [PDF]
Frontiers in Reproductive HealthBackgroundPolycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder characterized by polycystic ovaries, oligoanovulation, hyperandrogenism and infertility.
Marieme Elwafi +8 more
doaj +2 more sources
Luteinizing hormone/choriogonadotropin receptor (LHCGR; LHR) [PDF]
Science-Business eXchange, 2009 openalex +3 more sources
Quantitative ELISAs for serum soluble LHCGR and hCG-LHCGR complex: potential diagnostics in first trimester pregnancy screening for stillbirth, Down’s syndrome, preterm delivery and preeclampsia [PDF]
Reproductive Biology and Endocrinology, 2012 Background Soluble LH/hCG receptor (sLHCGR) released from placental explants and transfected cells can be detected in sera from pregnant women. To determine whether sLHCGR has diagnostic potential, quantitative ELISAs were developed and tested to examine
Chambers Anne E +7 more
doaj +4 more sources
A novel variant luteinizing hormone receptor in the first transmembrane helix of two homozygous Iranian patients: case report [PDF]
Egyptian Journal of Medical Human Genetics, 2022 Background Leydig cell hypoplasia (LCH) is a rare autosomal recessive endocrine syndrome that affects the normal development of male external genitalia in 46, XY individuals and is one of the causes of disorder of sexual differentiation (DSD) in males ...
Samaneh Sharif +6 more
doaj +5 more sources