Results 31 to 40 of about 11,867 (232)

Expression profiles of the glucose-dependent insulinotropic peptide receptor and LHCGR in sporadic adrenocortical tumors [PDF]

Journal of Endocrinology, 2008
Glucose-dependent insulinotropic peptide receptor (GIPR) and LHCGR are G-protein-coupled receptors with a wide tissue expression pattern. Aberrant expression of these receptors has rarely been demonstrated in adult sporadic adrenocortical tumors with a lack of data on pediatric tumors. We quantified the GIPR and LHCGR expression in a large cohort of 55
Márcia Helena Soares Costa, Ana Claudia Latrônico, Regina Matsunaga Martin, Angela Silva Barbosa, Madson Q. Almeida, Claudimara Ferini Pacicco Lotfi, Helena Panteliou Lima Valassi, Mirian Yumie Nishi, Antonio Marmo Lucón, Sheila Aparecida Coelho Siqueira, Maria Cláudia Nogueira Zerbini, Luciani R. Carvalho, Berenice B. Mendonça, Maria Candida Barisson Villares Fragoso   +13 more
openalex   +4 more sources

Significance of LHCGR polymorphisms in polycystic ovary syndrome: an association study

Scientific Reports, 2023
AbstractThis study was conducted to analyze the association of Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) gene rs4953616 and rs7371084 polymorphisms with the risk of polycystic ovary syndrome (PCOS) in Punjab, India. A total of 823 women (443 PCOS cases and 380 healthy controls) were enrolled in the present study.
Sukhjashanpreet Singh, Mandeep Kaur, Archana Beri, Anupam Kaur   +3 more
openaire   +3 more sources

The utility of circulating LHCGR as a predictor of Down's syndrome in early pregnancy [PDF]

BMC Pregnancy and Childbirth, 2014
Previous studies showed that soluble LHCGR/hCG-sLHCGR concentrations in serum or plasma combined with PAPP-A and free βhCG significantly increased the sensitivity of Down's syndrome screen at early pregnancy without altering the false positive rate. The goal of the present study was to further examine the role of sLHCGR forms as combinatorial markers ...
Michael Pugia, Imma Mercadé, Laia Rodriguez-Revenga Bodi, Francesca Crovetto, Aurea Mira, Eduard Gratacós, Luis Lasalvia, Anne E. Chambers, Subhasis Banerjee, Fatima Crispi, Walter E Mills, Elena Casals   +11 more
openaire   +3 more sources

The G-protein coupled estrogen receptor (GPER/GPR30) is a gonadotropin receptor dependent positive prognosticator in ovarian carcinoma patients. [PDF]

PLoS ONE, 2013
Follicle stimulating hormone receptor (FSHR) and luteinizing hormone receptor (LHCGR) were demonstrated to impact upon survival of patients suffering from epithelial ovarian cancer (EOC).
Sabine Heublein, Doris Mayr, Thomas Vrekoussis, Klaus Friese, Simone S Hofmann, Udo Jeschke, Miriam Lenhard   +6 more
doaj   +1 more source

Pilot study on evaluation and determination of the prevalence of Polycystic Ovarian Syndrome (PCOS) associated gene markers in the South Indian population

Indian Journal of Endocrinology and Metabolism, 2021
Background: Polycystic ovarian syndrome (PCOS) is typically characterized by a spectrum of manifestations that include menstrual irregularities, anovulation, cysts, hyperandrogenic features like hirsutism, acne, alopecia, and various metabolic ...
Balaji Ramanathan, Jeyasudha Murugan, Kumaravel Velayutham   +2 more
doaj   +1 more source

Expression and function of the luteinizing hormone choriogonadotropin receptor in human endometrial stromal cells

Scientific Reports, 2022
The human luteinising hormone choriogonadotropin receptor (LHCGR) is a G-protein coupled receptor activated by both human chorionic gonadotropin (hCG) and luteinizing hormone (LH), two structurally related gonadotropins with essential roles in ovulation ...
O. N. Mann, C.-S. Kong, E. S. Lucas, J. J. Brosens, A. C. Hanyaloglu, P. J. Brighton   +5 more
doaj   +1 more source

Mutations in a novel, cryptic exon of the luteinizing hormone/chorionic gonadotropin receptor gene cause male pseudohermaphroditism. [PDF]

PLoS Medicine, 2008
Male pseudohermaphroditism, or Leydig cell hypoplasia (LCH), is an autosomal recessive disorder in individuals with a 46,XY karyotype, characterized by a predominantly female phenotype, a blind-ending vagina, absence of breast development, primary ...
Nina Kossack, Manuela Simoni, Annette Richter-Unruh, Axel P N Themmen, Jörg Gromoll   +4 more
doaj   +1 more source

Diagnosis and treatment of familial male precocious puberty caused by LHCGR gene mutation: two case reports and literature review [PDF]

Zhenduanxue lilun yu shijian, 2022
Objective: To report the clinical features, gene detection results and treatment results of two patients with familial male limited precocious puberty(FMPP). Methods: Detailed medical history collection and physical examination were carried out in 2 FMPP
HE Qinyu, WANG Wei, CHEN Lifen, ZHANG Xuelei, DONG Zhiya
doaj   +1 more source

Proliferation of Luteal Steroidogenic Cells in Cattle [PDF]

, 2013
The rapid growth of the corpus luteum (CL) after ovulation is believed to be mainly due to an increase in the size of luteal cells (hypertrophy) rather than an increase in their number.
Abe, Hironori, Okuda, Kiyoshi, Sakumoto, Ryosuke, Yoshioka, Shin   +3 more
core   +8 more sources

Microvesicle-mediated release of soluble LH/hCG receptor (LHCGR) from transfected cells and placenta explants

Reproductive Biology and Endocrinology, 2011
Placental hCG and pitutary LH transduce signals in target tissues through a common receptor (LHCGR). We demonstrate that recombinant LHCGR proteins which include the hormone-binding domain are secreted from transfected cells and that natural LHCGR is ...
Randeva Harpal, Stanley Paul F, Chambers Anne E, Banerjee Subhasis   +3 more
doaj   +1 more source