Results 31 to 40 of about 12,270 (235)

Significance of FSHR and LHCGR gene polymorphisms on clinical outcomes in gonadotropin-releasing hormone antagonist protocol with freeze-all strategy: A case-control study

International Journal of Reproductive BioMedicine
Background: Follicle-stimulating hormone receptor (FSHR) and luteinizing hormone/choriogonadotropin receptor (LHCGR) are integral to ovarian function, facilitating follicle development and maturation through their respective hormonal interactions.
Jayesh Amin, Naga Sandhya Alle, Ami Patel, Bansi Prajapathi, Paresh Makwana, Jaya Prakash, Kota Murali Krishna   +6 more
doaj   +2 more sources

Inherited mutation of the luteinizing hormone/choriogonadotropin receptor (LHCGR) in empty follicle syndrome [PDF]

Fertility and Sterility, 2011
To test by genomic analysis whether empty follicle syndrome (EFS) in a family with two affected sisters has a genetic basis.Whole-exome sequencing in the context of clinical genetics.University hospital.Two women (36 and 32 years old at the time of the study) with EFS.Genetic counseling based on autosomal recessive inheritance.Discovery of a mutation ...
Kemal O. Yariz, Tom Walsh, Aslı Subasioglu Uzak, Michail Spiliopoulos, Duygu Duman, Göğşen Önalan, Mary‐Claire King, Mustafa Tekin   +7 more
  +7 more sources

MeCP2 duplication causes hyperandrogenism by upregulating LHCGR and downregulating RORα [PDF]

Cell Death & Disease, 2021
AbstractDuplication of MECP2 (methyl-CpG-binding protein 2) gene causes a serious neurological and developmental disorder called MECP2 duplication syndrome (MDS), which is usually found in males. A previous clinical study reported that MDS patient has precocious puberty with hyperandrogenism, suggesting increased MeCP2 may cause male hyperandrogenism ...
Yu-Meng Wang, Yu Wu, Yu-Fang Zheng, Hong-Yan Wang   +3 more
openaire   +3 more sources

Influence of VEGFR and LHCGR on endometrial adenocarcinoma

Oncology Letters, 2016
Endometrial adenocarcinoma is a common gynecological malignancy that is usually treated by surgical resection followed by radiation. However, the frequency of remote metastasis is high. The present study aimed to investigate whether patients with endometrial adenocarcinoma exhibited a positive response to treatment with a gonadotropin-releasing hormone
Alexandra C. Kölbl, Amelie Birk, Christina Kühn, Udo Jeschke, Ulrich Andergassen   +4 more
openalex   +5 more sources

A case of micropenis caused by compound heterozygote mutations in luteinizing hormone/choriogonadotropin receptor (LHCGR) [PDF]

Jichu yixue yu linchuang, 2022
Objective To investigate the pathogenic gene mutations and clinical characteristics in a patient with compound heterozygote gene mutations in luteinizing hormone/choriogonadotropin receptor (LHCGR) gene.
YANG Yu-fan, ZHAO Ya-ling, WANG Xi, NIE Min, WU Xue-yan, MAO Jiang-feng
doaj   +1 more source

Genotyping of cows by LHCGR, FSHR loci and determination of the level of ovulation depending on the expression of the studied genes

Open Veterinary Journal, 2023
Background: Genotyping offers a promising avenue for identifying the healthy reproductive system in cows. The healthy reproductive system in cows is determined by measuring the level of ovulation and by identifying the type polymorphism of specific ...
Yktiyar Sarybayev, Yessengali Ussenbekov, Orynbassar Turebekov, Bekbolat Bekbolat, Ibragim Tutkyshbay   +4 more
doaj   +1 more source

A delayed ovulation of Progestin-Primed Ovarian Stimulation (PPOS) by down-regulating the LHCGR/PGR pathway [PDF]

iScience, 2022
Abstract PPOS as a new clinic ovulation stimulation protocol, its role in ovulation and regulatory mechanism is not clear. The clinical PPOS protocol was simulated in mice, and it had a delayed ovulation than the control group at 12.5 hours after hCG trigger.
Yating Xie, Wenya Guo, Xi Shen, Weina Yu, Yanping Kuang, Qiuju Chen, Hui Long, Qifeng Lyu, Li Wang   +8 more
openalex   +4 more sources

Identification of key miRNAs as regulatory biomarkers of gonadotropins leading to infertility in males

Акушерство, гинекология и репродукция, 2023
Introduction. Infertility is a highly fatal reproductive system disorder that affects the ability of a couple to reproduce. Over the past decades, a drastic uplift has been recorded in infertility cases among males ranging from 20 to 70 % indicating ...
N. A. Oohayyed, M. M. Mohammed, A. M. Al-Rahim, R. N. Al Chalabi, S. A. Shaban, A. A. J. Suleiman   +5 more
doaj   +1 more source

Evidence for gating roles of protein kinase A and protein kinase C in estradiol-induced luteinizing hormone receptor (lhcgr) expression in zebrafish ovarian follicle cells. [PDF]

PLoS ONE, 2013
Estradiol (E2) stimulates luteinizing hormone receptor (lhcgr) expression in zebrafish follicle cells via nuclear estrogen receptors (nERs) that are likely expressed on the membrane, and lhcgr responds to E2 in a biphasic manner during 24-h treatment ...
Ka-Cheuk Liu, Wei Ge
doaj   +1 more source

OR35-04 Genetic Circuitry of LHCGR: a Modulator of Body Composition and Metabolic Traits in Humans [PDF]

J Endocr Soc
Hasni Kannangara, Ofer Moldavski, Anisa Gumerova, Uliana Cheliadinova, Georgii Pevnev, Parte Surabhi, Darya Vasilyeva, Leon I. Igel, Orly Barak, Shozeb Haider, Tony Yuen, Mone Zaidi, Daria Lizneva   +12 more
europepmc   +3 more sources