Cellular Physiology and Biochemistry, 2017 Background/Aims: Physiological role of luteinizing hormone (LH) and its receptor (LHCGR) in adrenal remains unknown. In inhibin-α/Simian Virus 40 T antigen (SV40Tag) (inhα/Tag) mice, gonadectomy-induced (OVX) elevated LH triggers the growth of ...
Milena Doroszko +10 more
doaj +1 more source
Short oestrous cycles in sheep during anoestrus involve defects in progesterone biosynthesis and luteal neovascularisation [PDF]
, 2014 Anoestrous ewes can be induced to ovulate by the socio-sexual, 'ram effect'. However, in some ewes the induced ovulation is followed by an abnormally short luteal phase causing a so called, "short cycle".
Acritopoulou +28 more
core +3 more sources
Functional Integration of Different-Sex Gonad Transplants Into the Adult Mouse Hypothalamic Pituitary Gonadal Axis. [PDF]
Adv Biol (Weinh)This study introduces and investigates different‐sex gonad transplants in a mouse model of gender‐affirming hormone therapy. Ovaries and testes implanted into gonadectomized adults exhibit gametogenesis and steroidogenesis independent of the sex of the host.
Pfau DR +8 more
europepmc +2 more sources
Leydig cell hypoplasia type 1 diagnosed in early childhood with inactivating mutation in LHCGR gene [PDF]
Oxford Medical Case Reports, 2021 ABSTRACT Leydig cell aplasia/hypoplasia is an autosomal recessive condition. In its complete form, these patients are 46XY but are cryptorchid and phenotypically female. Most cases reported in literature presented with in adolescence with pubertal delay.
Fatma Özgüç Çömlek +3 more
openaire +3 more sources
Functional Implications of LH/hCG Receptors in Pregnancy-Induced Cushing Syndrome [PDF]
, 2017 Context: Elevated human choriogonadotropin (hCG) may stimulate aberrantly expressed luteinizing hormone (LH)/hCG receptor (LHCGR) in adrenal glands, resulting in pregnancy-induced bilateral macronodular adrenal hyperplasia and transient Cushing syndrome (
Bertherat, Jerome +16 more
core +1 more source
Proliferation of Luteal Steroidogenic Cells in Cattle [PDF]
, 2013 The rapid growth of the corpus luteum (CL) after ovulation is believed to be mainly due to an increase in the size of luteal cells (hypertrophy) rather than an increase in their number.
Abe, Hironori +3 more
core +3 more sources
Acute hypoxia induced dysregulation of clock-controlled ovary functions
Frontiers in Physiology, 2022 High altitudes or exposure to hypoxia leads to female reproductive disorders. Circadian clocks are intrinsic time-tracking systems that enable organisms to adapt to the Earth’s 24-h light/dark cycle, which can be entrained by other environmental stimuli ...
Mengnan Ding +24 more
doaj +1 more source
Pharmacogenomic and structural analysis of constitutive G-protein coupled receptor activity [PDF]
, 2007 Premi a l'excel·lència investigadora. Àmbit de les Ciències de la Salut. 2008G-protein coupled receptors (GPCRs) respond to a chemically diverse plethora of signal transduction molecules.
Aldo Jongejan +29 more
core +3 more sources
LH and hCG action on the same receptor results in quantitatively and qualitatively different intracellular signalling. [PDF]
PLoS ONE, 2012 Human luteinizing hormone (hLH) and chorionic gonadotropin (hCG) act on the same receptor (LHCGR) but it is not known whether they elicit the same cellular and molecular response.
Livio Casarini +7 more
doaj +1 more source
Targeted gene expression profiling in European sea bass (Dicentrarchus labrax, L.) follicles from primary growth to late vitellogenesis [PDF]
, 2011 7 páginas, 6 figuras, 1 tabla como material suplementario.A real-time PCR-based gene expression survey was performed on isolated European sea bass follicles from primary growth to late vitellogenesis. Expression levels of 18 transcripts with demonstrated
Behmenburg, Clemens +3 more
core +1 more source