Results 131 to 140 of about 2,351,922 (324)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Intellectual freedom principles for academic libraries : an interpretation of the Library Bill of Rigths

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 1999
Declaració sobre els principis generals de llibertat intel•lectual que s’han d’aplicar a una biblioteca universitària.
Association of College and Research Libraries
doaj  

Special Libraries, September 1973 [PDF]

open access: yes, 1973
Volume 64, Issue 9https://scholarworks.sjsu.edu/sla_sl_1973/1006/thumbnail ...
Special Libraries Association
core   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Special Libraries, September 1937 [PDF]

open access: yes, 1936
Volume 28, Issue 7https://scholarworks.sjsu.edu/sla_sl_1937/1006/thumbnail ...
Special Libraries Association
core   +2 more sources

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

Automated Inference of Software Library Usage Patterns [PDF]

open access: yesarXiv, 2016
Modern software systems are increasingly dependent on third-party libraries. It is widely recognized that using mature and well-tested third-party libraries can improve developers' productivity, reduce time-to-market, and produce more reliable software. Today's open-source repositories provide a wide range of libraries that can be freely downloaded and
arxiv  

Special Libraries, April 1934 [PDF]

open access: yes, 1932
Volume 25, Issue 4https://scholarworks.sjsu.edu/sla_sl_1934/1003/thumbnail ...
Special Libraries Association
core   +4 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

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