Results 41 to 50 of about 4,420,672 (386)

DNA-Encoded Chemical Libraries: A Selection System Based on Endowing Organic Compounds with Amplifiable Information.

open access: yesAnnual Review of Biochemistry, 2018
The discovery of organic ligands that bind specifically to proteins is a central problem in chemistry, biology, and the biomedical sciences. The encoding of individual organic molecules with distinctive DNA tags, serving as amplifiable identification bar
D. Neri, R. Lerner
semanticscholar   +1 more source

Special Libraries, December 1947 [PDF]

open access: yes, 1946
Volume 38, Issue 10https://scholarworks.sjsu.edu/sla_sl_1947/1009/thumbnail ...
Special Libraries Association
core   +3 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Streamlining Workflows in the Now: Using Evidence to Select a DVD Vendor for the University of Alberta Libraries

open access: yesEvidence Based Library and Information Practice, 2015
No abstract.
Jessica Thorlakson   +2 more
doaj   +1 more source

Special Libraries, September 1933 [PDF]

open access: yes, 1932
Volume 24, Issue 8https://scholarworks.sjsu.edu/sla_sl_1933/1007/thumbnail ...
Special Libraries Association
core   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

VLA Paraprofessional Forum 2011 Conference Report: Libraries: Paving the Way for Success

open access: yesVirginia Libraries, 2011
The nineteenth annual Virginia Library Association Paraprofessional Forum Conference was held May 22–24, 2011, at the Holiday Inn Select/Koger South Conference Center in Chesterfield County.
Virginia Libraries
doaj  

Designing the Cyberinfrastructure for Spatial Data Curation, Visualization, and Sharing

open access: yesIASSIST Quarterly, 2017
Widely used across disciplines such as natural resources, social sciences, public health, humanities, and economics, spatial data is an important component in many studies and has promoted interdisciplinary research development.
Yue Li, Nicole Kong, Stanislav Pejša
doaj   +1 more source

Special Libraries, September 1967 [PDF]

open access: yes, 1967
Volume 58, Issue 7https://scholarworks.sjsu.edu/sla_sl_1967/1006/thumbnail ...
Special Libraries Association
core   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Home - About - Disclaimer - Privacy