Results 101 to 110 of about 887,740 (305)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Membership of the Library and Information Association of South Africa (LIASA) among library and information science workers in KwaZulu-Natal

open access: yesSouth African Journal of Libraries and Information Science, 2009
A study was undertaken in 2007 among library and information service (LIS) workers in KwaZulu-Natal (KZN) to investigate LIASA membership trends. The objectives of the study were to investigate: 1) the extent to which workers in library and information ...
Musa Khomo, Jaya Raju
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Pakistan Library Association

open access: yesPakistan Journal of Information Management & Libraries, 2008
This paper traces the history of the initiative that led to the formation of the Pakistan Library Association and deals with the difficulties it faced in its functioning during the first few years of its life. It uses primary documents dealing with this
Mumtaz A. Anwar
doaj  

Directives européennes sur le droit d’auteur et les droits voisins [PDF]

open access: yes
EBLIDA, acronyme anglais pour European Bureau of Libraries, Documentation and Archives Associations, a été créée en 1992, afin de coordonner les actions des associations de bibliothécaires ou de documentalistes à l’échelon européen.
Belayche, Claudine
core   +1 more source

The Activities and Program of the American Association of Law Libraries [PDF]

open access: yes, 1936
Denna rapport kommer att behandla konstruktion och design av ett småskaligt portabelt solvärmesystem. Rapportens första del är en teoretisk referensram som ligger till grund för byggandet av en prototyp av den behandlade solvärmetypen som har testats för
Klasson, Hanna   +4 more
core   +1 more source

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