Results 101 to 110 of about 1,469,506 (316)
Molecular Oncology, EarlyView.Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source
JLIS.it, 2013 Interoperability today is the key term for the enhancement of databases published on the web: the data, when isolated, have little value, on the contrary, their value increases significantly when different datasets, produced and published independently ...
Tommaso Agnoloni +4 more
doaj +1 more source
From many records to one graph: Heterogeneity conflicts in the Linked data restructuring cycle [PDF]
, 2013 Introduction. During the last couple of years the library community has developed a number of comprehensive metadata standardization projects inspired by the idea of linked data, such as the BIBFRAME model.
Tallerås, Kim
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Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Dynamic map display in library web OPAC [PDF]
, 2007 Peer reviewedJournal ArticleAdding more features to the web OPAC or making the Integrated Library Management systems (ILMS) more compatible to external web services has been a tendency in recent years.
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Molecular Oncology, EarlyView.In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
The library catalogue and the linked data
Em Questão, 2017 The article aims to discuss the possibilities of applying semantic web concepts in the library catalogue, through the application of linked data, favoring the exchange of dynamic information, readable by people and machines. The method adopted is an exploratory research through literature, with a selection of texts that discuss the catalogues, semantic
Serra, Liliana Giusti +1 more
openaire +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Algunas problemáticas relacionadas con las TICs y la bibliotecología [PDF]
, 2004 This paper addresses some issues about the Information and Communication Technologies (ICTs) not much discussed on the library and information science (LIS) field in Latin America.
Lencinas, Verónica
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