Results 81 to 90 of about 50,365,614 (272)

Modelling Library Linked Data In Practice

, 2015
In this paper we present reflections and recommendations concerning the conversion of library metadata into Linked Data. We will briefly describe the different data models that exist for this purpose and argue their strengths and weaknesses with a special focus on the entification issue, before illustrating this problem with the description of three ...
Prongué, Nicolas , Schneider, René
openaire   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Linked Data in Library Workflows

, 2023
As the library community continues to explore linked data for cataloging and data management, there are a variety of new opportunities as well as challenges to ensure that data is interoperable and manageable across bibliographic datasets.
Evans, Rachel, Mixter, Jeff
core   +2 more sources

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Linked Data in the UNT Libraries' Digital Collections

, 2015
Presentation for the Linked Data: An Emerging Trend Panel at the Texas Library Association (TLA) 2015 Annual Conference.
Tarver, Hannah
core  

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Linked open government data: lessons from Data.gov.uk [PDF]

, 2012
The movement to publish government data is an opportunity to populate the linked data Web with data of good provenance. The benefits range from transparency to public service improvement, citizen engagement to the creation of social and economic value ...
Hall, Wendy, Gibbins, Nicholas, O'Hara, Kieron, schraefel, m.c., Berners-Lee, Tim, Shadbolt, Nigel, Glaser, Hugh   +6 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

The library catalogue and the linked data

, 2017
The article aims to discuss the possibilities of applying semantic web concepts in the library catalogue, through the application of linked data, favoring the exchange of dynamic information, readable by people and machines. The method adopted is an exploratory research through literature, with a selection of texts that discuss the catalogues, semantic
Serra, Liliana Giusti, Santarem Segundo, Jose Eduardo   +1 more
openaire   +2 more sources