Results 31 to 40 of about 50,365,614 (272)
DigitalLatin/linked-open-data: First release of LOD for DLL
, 2019 <p>This is the first release of data in the Linked Open Data repository for the Digital Latin Library Catalog.</p ...
Samuel J. Huskey
core +1 more source
, 2021 CSIRO Computational Informatics, Australian National University, Australia Information services are commonly provided via Web APIs based on Representational State Transfer (REST) principles [196,452] or via Web Services based on the WS-* technology ...
Junghans, Martin +2 more
core +1 more source
JLIS.it, 2013 ITACH@ Project, Innovative Technologies And Cultural Heritage Aggregation, intends to offer innovative tools for the development of the tourism industry and Italian culture. This paper analyzes the particular technological component defined OpLiDaF, Open
Tiziana Possemato
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Relationship status: libraries and linked data in Europe [PDF]
, 2018 Libraries shared metadata long before the advent of the Internet by utilising standards such as MARC and AACR to enable interoperability (Tallerås, 2013). A difficulty with their use in the networked environment has been the inability to exchange data at scale, due to the diversity of descriptive standards and schemas adopted as well as the diversity ...
Rasmussen Pennington, Diane +1 more
openaire +2 more sources
Applying linked data in multimedia annotations [PDF]
, 2012 Current multimedia applications in Web 2.0 have generated large repositories for multimedia resources and annotations, so there is an urgent requirement to interlink annotations of these resources across different repositories to achieve better indexing ...
YUNJIA LI +5 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source