Results 41 to 50 of about 491,826 (279)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
JLIS.it, 2013 This paper will focus on the application profiles recently implemented in the new Vatican Library's discovery tool that interacts with interoperability standards and manages different metadata.
Paola Manoni
doaj +1 more source
Highlights of Library Data Models in the Era of Linked Open Data [PDF]
, 2013 Semantic Web technologies and Linked data form a new reference framework for libraries. The library community aims to integrate its data with the Semantic Web and as a result new library data models have been developed. In this context, significant research effort focuses on the alignment between the library models with relevant models developed by ...
Sofia Zapounidou +2 more
openaire +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Il Nuovo soggettario come servizio per il mondo dei linked data
JLIS.it, 2012 Nuovo soggettario (NS), edited by the National Central Library of Florence, is the Italian subject indexing tool for various types of resources. It has been developed in compliance with the IFLA recommendations, and other international standards in the ...
Giovanni Bergamin, Anna Lucarelli
doaj +1 more source
Best Practices for Library Linked Open Data (LOD) Publication
, 2021 The original mission statement of LIBER’s Linked Open Data Working Group is to produce guidelines and best practices for libraries wishing to open their data in linked format.
Hansson, David +11 more
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Linked Data in Library Workflows
NASIG ProceedingsAs the library community continues to explore linked data for cataloging and data management, there are a variety of new opportunities as well as challenges to ensure that data is interoperable and manageable across bibliographic datasets. Data model interoperability is critical to ensure we can continue to manage bibliographic materials at scale ...
Anne Washington, Jeff Mixter
openaire +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source