Results 81 to 90 of about 9,043,325 (397)
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Stemming of Slovenian library science texts
Knjižnica, 2002 The theme of the article is the preparation of a stemming algorithm for Slovenian library science texts. The procedure consisted of three phases: learning, testing and evaluation.
Polona Vilar, Jasna Maver
doaj +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Implications for Library and Information Science Education [PDF]
, 1984 published or submitted for ...
Lancaster, F.W.
core
Data preservation, the new science and the practitioner librarian [PDF]
, 2007 This paper outlines the information management principles of the so-called 'new science', and attempts to put these in the context of traditional library and information science principles.
Joint, Nicholas
core +1 more source
Library Science Education in the U.S.A.
Bilgi Dünyası, 2001 Classical librarianship drowns in the sea of change. in the United States our profession had indicated a profound change -especially in the last 20 years.
Sommers Pierce
doaj +1 more source
Preface to Library Science [PDF]
Nature, 1949 THIS book is in the nature of a mixed grill for two. Based on the inaugural lectures delivered in the Department of Library Science in the University of Delhi in 1947 it consists, in part, of an attempt to establish that there is a library science and, in part, of a practical exposition to students of what Dr. S. R.
openaire +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Tratat de biblioteconomie [Library Science Treatise]
Revista Română de Biblioteconomie și Știința Informării, 2017 Tratat de biblioteconomie. Coord. gen.: Mircea Regneală. Bucureşti: Asociaţia Bibliotecarilor din România, 2013-2017. ISBN 978-606-93535-0-9 Vol. 1: Biblioteconomie generală [Fundamentals of Library Science]. Coord.: Mircea Regneală. 2013.
Corina Apostoleanu
doaj +1 more source