Advanced Science, EarlyView.Glucocorticoids (GC) are widely used to reduce inflammation. We show that the glucocorticoid receptor in myeloid cells regulates macrophage cell cycle and genome integrity during muscle regeneration. We demonstrate that dexamethasone administration during the early inflammatory phase delays muscle repair by increasing macrophage proliferation ...
Sirine Souali‐Crespo +11 more
wiley +1 more source
A minimal hybridization capture approach for the parallel enrichment and cost-effective detection of ancient human pathogens. [PDF]
iScienceKocher A +8 more
europepmc +1 more source
Engineered Transformer Base Editor with Enhanced Editing Efficiency
Advanced Science, EarlyView.A highly efficient transformer base editor system achieves robust genomic editing in a humanized mouse model. This work establishes a versatile and translatable platform, opening new avenues for precision gene therapy. ABSTRACT Canonical cytosine base editors (CBEs) achieve precise C‐to‐T conversions without inducing DNA double‐strand breaks (DSBs ...
Bowen Chen +5 more
wiley +1 more source
Book Review: Information Literacy Collaborations that Work
Partnership: The Canadian Journal of Library and Information Practice and Research, 2007 Laura Emery
doaj +1 more source
Chromosome-level genome assembly of the Erythrina gall wasp, Quadrastichus erythrinae (Hymenoptera: Eulophidae). [PDF]
G3 (Bethesda)Zhang YM +5 more
europepmc +1 more source
Seeing the Chemistry of Biomolecular Condensates: In Situ Mapping of Composition and Water Content
Advanced Science, EarlyView.Raman hyperspectral imaging combined with spectral phasor analysis enables a label‐free quantification of proteins, polymers and water density within individual biomolecular condensates. By transforming complex vibrational fingerprints into intuitive compositional maps, the approach reveals the high water content and structural heterogeneity of ...
E. Sabri +3 more
wiley +1 more source
Book Review: Answering Consumer Health Questions
Partnership: The Canadian Journal of Library and Information Practice and Research, 2008 Laura Emery
doaj +1 more source
Multidimensional factors influencing continuance usage intention of university library self-service systems: An empirical analysis based on an extended TAM-UTAUT. [PDF]
PLoS OneCao K, Wang P, Zhang C, Zhao J.
europepmc +1 more source
PhysiomeSpace: digital library service for biomedical data. [PDF]
Philos Trans A Math Phys Eng Sci, 2010 Testi D, Quadrani P, Viceconti M.
europepmc +1 more source
Mapping Embryonic Mouse Lung Development Using Enhanced Spatial Transcriptomics
Advanced Science, EarlyView.The mammalian lung contains ∼50 cell types arranged along the airway epithelium. Here, deterministic barcoding sequencing (DBiT‐seq) is optimized to nearly double transcript recovery, enabling highly sensitive spatial mapping of the embryonic mouse lung.
Pengfei Zhang +5 more
wiley +1 more source