Results 51 to 60 of about 299,152 (273)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Hyers–Ulam Stability of Solution for Generalized Lie Bracket of Derivations

Journal of Mathematics
In this work, we present a new concept of additive-Jensen s-functional equations, where s is a constant complex number with ...
Vahid Keshavarz, Mohammad Taghi Heydari
doaj   +1 more source

Lie Derivations on Generalized Matrix Algebras by Local Actions

Axioms
Let G=G(A,B,M,N) be a generalized matrix algebra. A linear map Δ:G→G is called a Lie derivation at E∈G if Δ([U,V])=[Δ(U),V]+[U,Δ(V)] for all pairs U,V∈G such that UV=E.
Jinhong Zhuang, Yanping Chen, Yijia Tan
doaj   +1 more source

Derivations satisfying certain algebraic identities on Lie ideals [PDF]

Mathematica Moravica, 2019
Let d be a derivation of a semiprime ring R and L a nonzero Lie ideal of R. In this note, it is proved that every noncentral square-closed Lie ideal of R contains a nonzero ideal of R. Further, we use this result to characterize the conditions: d(xy) = d(
Sandhu Gurninder S., Kumar Deepak
doaj  

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Action of multiplicative (generalized)-derivations and related maps on square closed Lie ideals in prime rings

Математичні Студії
Let $\mathcal{R}$ be a prime ring and $L$ a nonzero square closed Lie ideal of $\mathcal{R}$. Suppose $F,G,H\colon \mathcal{R}\to \mathcal{R}$\break are three multiplicative (generalized)-derivations associated with the maps $\delta,g, h\colon \mathcal{R}
B. Dhara
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Characterization of Nonlinear Mixed Bi-Skew Lie Triple Derivations on ∗-Algebras

Mathematics
This paper concentrates on examining the characterization of nonlinear mixed bi-skew Lie triple ∗- derivations within an ∗-algebra denoted by A which contains a nontrivial projection with a unit I.
Turki Alsuraiheed, Junaid Nisar, Nadeem ur Rehman   +2 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source