Association between Life's Crucial 9 and Cardiorenal syndrome: the mediating role of weight-adjusted-waist index. [PDF]
BackgroundRecent studies have indicated a link between cardiovascular wellbeing, obesity, and Cardiorenal syndrome (CRS). The impact of excessive body mass on the dynamics between heart health and CRS remains unclear.
Fu H +6 more
europepmc +4 more sources
Curvilinear relationship between life's crucial 9 and metabolic syndrome in U.S. adults: a cross-sectional study. [PDF]
BackgroundMetabolic Syndrome (MetS) is closely linked to cardiovascular disease. However, no studies have examined the relationship between Life’s Crucial 9 (LC9) and MetS.
Wang B +5 more
europepmc +4 more sources
Neutrophil-to-Albumin Ratio Mediates the Association Between Life's Crucial 9 and Sarcopenia: A Cross-Sectional Study. [PDF]
Background Emerging evidence links cardiovascular health, inflammation, and sarcopenia (SP), but the mediating mechanisms remain unclear. Life's Crucial 9 (LC9), a novel metric integrating mental health with cardiovascular risk factors, and neutrophil‐to‐
He Q, Liu Y, Li Y, Wang Y.
europepmc +3 more sources
Comparative Discrimination of Life's Simple 7, Life's Essential 8, and Life's Crucial 9: Evaluating the impact of added complexity on mortality prediction. [PDF]
Background Cardiovascular health (CVH) is a key determinant of mortality, but the comparative effectiveness of different CVH metrics remains uncertain.
Zhu X +8 more
europepmc +4 more sources
Composite cardiovascular health indices (Life's essential 8 and Life's crucial 9) and female infertility: an NHANES 2013-2018 cross-sectional analysis. [PDF]
BackgroundFemale infertility affects 10–15% of couples worldwide and is influenced by multiple factors, including cardiovascular and metabolic health. This study examines the association between composite cardiovascular health indices—Life’s Essential 8 (
Duan Y, Liu P, Li H, Gao Y.
europepmc +4 more sources
Neutrophil-to-albumin ratio mediates the association between Life's Crucial 9 and chronic obstructive pulmonary disease. [PDF]
BackgroundChronic obstructive pulmonary disease (COPD) is a progressive respiratory disorder characterized by persistent airflow limitation and chronic airway inflammation.
Feng J, Gong H.
europepmc +4 more sources
The curvilinear associations between Life's Crucial 9 and frailty: cross-sectional study of NHANES 2003 - 2023. [PDF]
BackgroundFrailty not only affects disease survival rates but also the quality of life. The Life’s Crucial 9 (LC9) is a recently proposed cardiovascular health risk score that incorporates mental health along with Life’s Essential 8 (LE8).
Wang B +6 more
europepmc +4 more sources
Association between Life's Crucial 9 and overactive bladder: the mediating role of weight-adjusted-waist index. [PDF]
BackgroundResearch suggests a potential connection between cardiovascular health, obesity, and overactive bladder (OAB). However, the mechanisms by which obesity influences the relationship between cardiovascular health and OAB remain unclear.
Gong H, Duan S, Huang S.
europepmc +4 more sources
Associations of cardiovascular health assessed by life's crucial 9 with incident cardiovascular disease and dementia: A prospective cohort study. [PDF]
Background: The associations of the renewed cardiovascular health (CVH) assessed by Life’s Crucial 9 (LC9), which consisted of Life’s Essential 8 (LE8) and psychological health, with incident cardiovascular disease (CVD) and dementia remained unexplored.
Dai Y +14 more
europepmc +4 more sources
Central adiposity indices and inflammatory markers mediate the association between life's crucial 9 and periodontitis in US adults. [PDF]
Background Periodontitis, a chronic inflammatory disease, is closely linked to cardiovascular health. While Life’s Essential 8 (LE8) evaluates cardiovascular metrics, recent recommendations suggest incorporating psychological health (PHQ-9) to form Life ...
Guo JJ +10 more
europepmc +4 more sources

