Association of Life's Crucial 9 with cognitive function and stroke risk: insights from the NHANES 2011-2014 study. [PDF]
BMC Public HealthBackground Cognitive impairment and stroke constitute major health challenges for the aging global population, adversely impacting quality of life and increasing healthcare burdens.
Liu R, Feng J, Ma J, Chen X.
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Life's Crucial 9 and psoriasis: a mediation analysis of systemic inflammation response index using NHANES cohort data. [PDF]
Front ImmunolBackgroundPsoriasis is a chronic, recurrent, inflammatory disease. The aim of this study was to investigate the association between the Life’s Crucial 9 (LC9) score and the risk of psoriasis and to examine the mediating role of system inflammation ...
Liu X, Deng Q, Tang H.
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Association of the "life's crucial 9" cardiovascular health with all-cause and cardiovascular disease mortality: a national cohort study. [PDF]
Arch Public HealthBackground In 2022, the American Heart Association launched an updated algorithm for quantifying cardiovascular health (CVH), termed Life’s Essential 8 (LE8). This new approach has been shown to be associated with various noncommunicable chronic diseases
Tu D, Xu Q, Sun J, Li P, Ma C.
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Commentary: Association between Life's Crucial 9 and overactive bladder: the mediating role of weight-adjusted-waist index. [PDF]
Front NutrDu R, Su Y, Zhang P.
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Lifestyle, Inflammation, and Periodontitis: A National Study Based on the Life's Crucial 9 Framework. [PDF]
Oral Health Prev DentTo examine the association between the Life's Crucial 9 (LC9) lifestyle score and periodontitis severity among U.S. adults, and to explore the mediating roles of systemic inflammation and oxidative stress. The study hypothesis is that higher LC9 scores are associated with lower periodontitis severity.This cross-sectional study used data from 7124 ...
Jia B +5 more
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Association between Life's Crucial 9 and sarcopenia: The mediating role of testosterone partially. [PDF]
Medicine (Baltimore)Sarcopenia, an age-related decline in skeletal muscle mass and function, is influenced by modifiable lifestyle factors. Life’s Crucial 9 (LC9), a composite cardiovascular health metric, may mitigate sarcopenia risk, potentially mediated by testosterone. However, population-level evidence and mechanistic insights remain limited.
You B, Chen Z.
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Predictive Value of Life's Crucial 9 for Cardiovascular and All-Cause Mortality: A Prospective Cohort Study From the NHANES 2007 to 2018. [PDF]
J Am Heart AssocBackground The predictive value of Life's Crucial 9 (LC9), a recently proposed cardiovascular health risk score combining psychological health and Life's Essential 8 (LE8), remains unclear.
Ge J, Peng W, Lu J.
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The Inverse Association of Psoriasis and Life's Crucial 9 in US Adults: An Analysis from NHANES. [PDF]
J Multidiscip HealthcLife's Crucial 9 (LC9) is a new tool used to evaluate cardiovascular health. At present, no studies have reported the association between LC9 and psoriasis.This cross-sectional study utilized data from the National Health and Nutrition Examination Survey (NHANES) conducted between 2009 and 2014.
Hao JC, Dou DN, Cheng SW, Gou RY.
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Life's Crucial 9 Score as a Novel Role for Chronic Obstructive Pulmonary Disease Screening. [PDF]
Int J Chron Obstruct Pulmon DisThis study aims to investigate the association between the Life's Crucial 9 (LC9) score and chronic obstructive pulmonary disease (COPD) in middle-aged and older adults.We screened the NHANES database for data from 2007-2018. Logistic regression analysis and subgroup analysis were used to explore the association between LC9 score and COPD in middle ...
Li W +5 more
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Life's crucial 9, plasma proteomics, and the risk of major complications and mortality in MASLD. [PDF]
NPJ Metab Health DisMetabolically dysfunction-associated steatotic liver disease (MASLD) constitutes a major health burden. Whether a multidomain profile of modifiable health, as captured by Life’s Crucial 9 (LC9), is associated with major complications in MASLD, and which ...
Zhang BY +15 more
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