Comparing the predictive accuracy of life’s essential 8 and life’s crucial 9 scores for all-cause mortality in COPD patients among US adults: a prospective cohort study [PDF]
Background Life’s Essential 8 (LE8) represents an established score for quantifying cardiovascular health (CVH). Life’s Crucial 9 (LC9) is a newly proposed metric that integrates psychological health with LE8.
Shuhui Qiu +5 more
doaj +3 more sources
Comparative Discrimination of Life’s Simple 7, Life’s Essential 8, and Life’s Crucial 9: Evaluating the impact of added complexity on mortality prediction [PDF]
Background Cardiovascular health (CVH) is a key determinant of mortality, but the comparative effectiveness of different CVH metrics remains uncertain.
Xu Zhu +8 more
doaj +3 more sources
Association between life’s crucial 9 and lung health: a population-based study [PDF]
Background As a cardiovascular health (CVH) assessment tool, Life’s Crucial 9 (LC9) is often associated with diverse chronic health indicators. However, no study has yet explored the association of LC9 with multifactorial components of lung health. Thus,
Haolin Shi, Xiuhua Ma
doaj +3 more sources
The role of Life’s Crucial 9 in cardiovascular disease incidence and dynamic transitions to dementia [PDF]
Background Cardiovascular disease (CVD) often coexists with dementia as the contributor to disease burden in the aging population. Although the effects of several modifiable factors on the CVD and dementia risk have been increasingly recognized, their ...
Yanyu Zhang +7 more
doaj +3 more sources
Composite cardiovascular health indices (Life’s essential 8 and Life’s crucial 9) and female infertility: an NHANES 2013–2018 cross−sectional analysis [PDF]
BackgroundFemale infertility affects 10–15% of couples worldwide and is influenced by multiple factors, including cardiovascular and metabolic health. This study examines the association between composite cardiovascular health indices—Life’s Essential 8 (
Yukun Duan +3 more
doaj +4 more sources
Associations of life’s crucial 9 with mortality among older adults with frailty: a prospective cohort study from the NHANES 2007 to 2018 [PDF]
Background Frailty among the elderly represents a considerable public health issue linked to increased vulnerability and adverse outcomes. The Life’s Crucial 9 (LC9) score, which includes mental health assessments alongside traditional cardiovascular ...
Shaohua Yan +6 more
doaj +3 more sources
Central adiposity indices and inflammatory markers mediate the association between life’s crucial 9 and periodontitis in US adults [PDF]
Background Periodontitis, a chronic inflammatory disease, is closely linked to cardiovascular health. While Life’s Essential 8 (LE8) evaluates cardiovascular metrics, recent recommendations suggest incorporating psychological health (PHQ-9) to form Life ...
Jia-Jie Guo +10 more
doaj +3 more sources
Association of the “life’s crucial 9” cardiovascular health with all-cause and cardiovascular disease mortality: a national cohort study [PDF]
Background In 2022, the American Heart Association launched an updated algorithm for quantifying cardiovascular health (CVH), termed Life’s Essential 8 (LE8). This new approach has been shown to be associated with various noncommunicable chronic diseases
Dingyuan Tu +4 more
doaj +3 more sources
Neutrophil percentage-to-albumin ratio mediates the association between life’s crucial 9 with cardiorenal syndrome: a secondary data analysis from NHANES [PDF]
Background Several studies have suggested a potential link between cardiovascular health, inflammation, and cardiorenal syndrome (CRS). However, the exact mechanism by which inflammation affects the relationship between cardiovascular health and CRS ...
Zhe Fang, Jiawen Zhao, Hongyang Gong
doaj +3 more sources
Life’s crucial 9, plasma proteomics, and the risk of major complications and mortality in MASLD [PDF]
Metabolically dysfunction-associated steatotic liver disease (MASLD) constitutes a major health burden. Whether a multidomain profile of modifiable health, as captured by Life’s Crucial 9 (LC9), is associated with major complications in MASLD, and which ...
Bing-Yun Zhang +15 more
doaj +2 more sources

