Results 91 to 100 of about 102,456 (227)
The middle years of Martin Amis [PDF]
, 2006 This essay was commissioned by Rod Mengham and Philip Tew for their volume British Fiction Today (London and New York: Continuum, 2006). Essays for this volume were specifically requested to focus on writers’ work since 1990.
Brooker, Joseph
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
BMC GeriatricsBackground Life’s Essential 8 (LE8), the recently updated construct for quantifying cardiovascular health, is related to the risks of cardiovascular events.
Yanli Zhang +13 more
doaj +1 more source
Associations between Life’s Essential 8 and liver function: a cross-sectional study
Frontiers in NutritionBackgroundLife’s Essential 8 (LE8) score, developed by the American Heart Association, assesses cardiovascular health using eight components: diet, physical activity, nicotine exposure, sleep health, body mass index, lipids, blood glucose, and blood ...
Qiaoli Liang, Menglong Zou, Ziming Peng
doaj +1 more source
INCREASING SERVICES QUALITY THROUGH ENVIRONMENTAL PERFORMANCE MANAGEMENT [PDF]
The qualitative dimension of the service companies’ activities also refers totheir impact over the environment. This aspect is meant to contribute to a sustainableeconomic growth, based on high economic performances, but also on obeying theenvironment ...
Camelia Burja, Vasile Burja
core
Understanding the Unique Needs of Adolescent Refugee Students [PDF]
, 2016 Using the Essential Attributes of developmentally responsive, challenging, empowering, and equitable guidelines established by This We Believe: Keys to Educating Young Adolescents, this article will provide a frame of reference for readers to assist ...
Bouton, Bobette
core +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
BMC GeriatricsBackground This study aimed to examine the association between the American Heart Association’s (AHA) newly revised Life’s Essential 8 (LE8) algorithm, designed for assessing cardiovascular health (CVH), and cognitive impairment among older adults in the
Hui Wang +6 more
doaj +1 more source