Results 81 to 90 of about 102,456 (227)

Leadership Development for Community Action: An Ethnographic Inquiry: Northwest Federation of Community Organizations [PDF]

, 2005
LeeAnn Hall directs the Northwest Federation of Community Organizations (NWFCO), a collaboration of four state-based community organizations engaged in the fight for social and economic justice. Leadership development is at the heart of the NWFCO mission
Lisa Weinberg
core  

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Association between Life’s Essential 8 and cataract among US adults

Scientific Reports
Currently, a comprehensive assessment of the relationship between ideal cardiovascular health (CVH) indicators and cataract risk is lacking. Life’s Essential 8 (LE8) is the latest concept proposed by the American Heart Association to comprehensively ...
Yang Meng, Zongbiao Tan, Abdulla Sawut, Lu Li, Changzheng Chen   +4 more
doaj   +1 more source

Long-Term Cardiovascular Health Trajectories Associated With Cardiovascular Disease and Mortality in Older Adults

JACC: Advances
Background: Maintaining cardiovascular health (CVH) is essential for preventing cardiovascular disease (CVD). Objectives: We aimed to evaluate associations of changes in CVH with CVD and mortality.
Yi Li, MA, Yunqing Han, MS, Yuanming Leng, MS, Madeleine Carbonneau, BS, Yanping Li, PhD, Daniel Levy, MD, Chunyu Liu, PhD, Jiantao Ma, PhD   +7 more
doaj   +1 more source

Origin of Life

, 2012
The evolution of life has been a big enigma despite rapid advancements in the fields of biochemistry, astrobiology, and astrophysics in recent years.
A. Gibbons, Ashwini Kumar Lal, C. Bohler, C. Chyba, C. Huber, C.E. Manning, C.J. Salter, D. Penny, D. Warmflash, D.S. Heckman, D.S. Mckay, E.G. Roussel, F. Hoyle, F. Hoyle, F. Hoyle, G.F. Joyce, H.C. Arp, H.C. Urey, J. Li, J. Maddox, J. Postgate, J.B.S. Haldane, J.K. Fredrickson, J.V. Narlikar, J.W. Schopf, K. Kvenvolden, L.-H. Lin, L.E. Orgel, L.J. Richardson, M.T. Mondigan, N.C. Wickramsinghe, P. David, P. Ehrenfreund, P. Senapathy, R. Shapiro, R.D. Lorenz, S Arrhenius, S.J. Mojzsis, S.L. Miller, S.L. Miller, Stofan, T. Brock, T.D. Brack, W. Gilbert, W. Martin, Y.-J. Kuan, Y.-J. Ma   +46 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Impact of migraine on changes in cardiovascular health profile among Hong Kong Chinese women: insights from the MECH-HK cohort study

The Journal of Headache and Pain
Background Previous research has shown an association between migraine and cardiovascular diseases (CVDs). However, limited studies have explored the progression of cardiovascular health (CVH) among individuals with migraine.
Jingbo Liang, Jia-Jun Ma, Harry Haoxiang Wang, Qingling Yang, Tongyu Ma, Qi Sun, Lin Yang, Yao Jie Xie   +7 more
doaj   +1 more source

Canadian Contributions to Social Reproduction Feminism, Race and Embodied Labor [PDF]

, 2008
Recent methodological advances in Canadian Social Reproduction Feminism foreground labor as a foundational concept of social theory and, as a result, address the structuralist bias critics of the paradigm have identified, while still grounding theory in ...
Ferguson, Sue
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source