Results 131 to 140 of about 20,559,883 (358)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

PROF. DR. NECATİ ÖNER'İN FELSEFE ANLAYIŞININ HAYAT KAVRAMI ÇERÇEVESİNDE BİR ANALİZİ

open access: yesFelsefe Dünyası, 2010
Bu makale felsefenin fert ve toplum hayatı açısından işlevi, hayatı anlama ve anlamlandırma konusundaki katkıları, Prof. Dr. Necati ÖNER'in felsefi düşünceleri çerçevesinde ele alınmış, onun felsefeye bakışı, eserlerinde ortaya koyduğu temel fikirleri ...
Abdulkuddüs Bingöl
doaj  

Global Life Satisfaction in Adolescence

open access: green, 2016
Jenny Marcionetti, Jérôme Rossier
openalex   +2 more sources

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

NİETZSCHE'DE BİLGİ-YAŞAM İLİŞKİSİ

open access: yesFelsefe Dünyası, 2008
Ogün ÜREK, "NİETZSCHE'DE BİLGİ-YAŞAM İLİŞKİSİ", FELSEFE DÜNYASI DERGİSİ, SAYI ...
Ogün Ürek
doaj  

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

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