Results 161 to 170 of about 1,301,937 (266)

Environmental footprint quantification and optimization methods for digital poster design based on life cycle assessment. [PDF]

PLoS One
Liu Y, Ji P.
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Life Cycle Assessment of HoLEP: Quantifying Environmental Impact and Opportunities for Sustainable Urologic Surgery. [PDF]

Eur Urol Open Sci
Klein C, Humbert V, Meune M, Tubiana-Dussin F, Charon S, Lamouroux K, Capon G, Alezra E, Estrade V, Blanc P, Margue G, Bernhard JC, Robert G, Bladou F.   +13 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Deriving proxy life cycle assessment datasets for manufacturing machines through data clustering. [PDF]

Int J Adv Manuf Technol
Dodd N, Koh L, Rothman R.
europepmc   +1 more source

The Protozoon Life-Cycle [PDF]

Science, 1906
openaire   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Phages for One Health: regulatory and product life cycle considerations. [PDF]

Microbiology (Reading)
Duignan L, Adriaenssens EM, Wright RCT, Sansom A, MacLeod I, Nagel TE, Jones JD, Fothergill JL, Coxon CH.   +8 more
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

The metabolic change trajectory of skeletal muscle during the life cycle: arteriovenous metabolomics. [PDF]

Life Med
Huang S, Gu Y, Xu G, Han J, Jia H, Wang Y, Chen X, Zhang N, Hua X, Mo H, Sun Z, Dong F, Chang Y, Cui H, Song J.   +14 more
europepmc   +1 more source