Results 61 to 70 of about 4,110,851 (310)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Income dynamics and the life cycle [PDF]

open access: yes, 2004
This paper argues that our understanding of income and poverty dynamics benefits from taking a life cycle perspective. A person¿s age and family circumstances ¿ the factors that shape their life cycle ¿ affect the likelihood of experiencing key life ...
Rigg, John A., Sefton, Tom
core  

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Artificial Intelligence Trends Based on the Patents Granted by the United States Patent and Trademark Office

open access: yesIEEE Access, 2020
This paper analyzes artificial intelligence (AI)-related patents that were granted by the U.S. Patent and Trademark Office (USPTO) between January 2008 and December 2018.
Hamidreza Habibollahi Najaf Abadi   +1 more
doaj   +1 more source

Measuring the Welfare Costs of Inflation in a Life-cycle Model [PDF]

open access: yes
In macroeconomics, life-cycle models are typically used to address exclusively life-cycle issues. This paper shows that modeling the life-cycle may be important when addressing public policy issues, in this case the welfare costs of inflation.
Paul Gomme
core  

Life Cycle Costing Applications in Sustainable Building [PDF]

open access: yes, 2009
Life Cycle Costing (LCC) which is defined ISO 15686-5:2005 is used to assess the sustainable and renewable technology used in building. The results indicate that the premium cost of sustainable/renewable technology in building is surprisingly lower than
Hartungi, Rusdy, Pye, Christopher John
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The Hydrolysis of Cow’s Rumen and Rice Straw Mixture using Sulfuric Acid and The Fermentation of Its Hydrolysate in Bioethanol Production [PDF]

open access: yesE3S Web of Conferences
This study aims to investigate the effect of cow’s rumen and rice straw ratio on hydrolysis as well as sulfuric acid concentration, temperature, and time were also examined.
Megawati   +14 more
doaj   +1 more source

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