Results 71 to 80 of about 1,301,937 (266)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Thesis on Firm Life Cycle, Product Life Cycle, and Retail Life Cycle

Management (Split), 1997
In this paper, the conceptions on firm life cycle, product life cycle and retail life cycle (institution and shop) have been analyzed. Conceptions based on biology have been compared as well. In retail forms specific qualities of particular approaches are described, connected with the efforts of a firm on that development, using price and other ...
openaire   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Wide-Range, Low-Hysteresis Soft Sensor with Architecture-Inspired Design Enabled by Femtosecond Laser-Induced Self-Growth

Sensors
Resolving the dichotomy between wide detection ranges and low mechanical hysteresis remains a critical challenge in flexible electronics, largely governed by the intrinsic viscoelastic creep of polymeric dielectrics.
Ziyue Yu, Changhao Ji, Xinyue Gao, Yu Li, Cheng Yang, Fawei Guo, Jianglin Fu, Yin Feng, Hongxuan Zhao, Yu Long   +9 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Quantifying Public Perceptions of Hydrogen Adoption in the United Kingdom Incorporating Challenges, Acceptance Factors and Proposed Strategies

Energy Science & Engineering
This study investigates the public acceptance of hydrogen technologies in the United Kingdom's domestic energy sector, with a focus on green and low‐carbon hydrogen as a pathway to decarbonisation.
Nikhil Ahlawat, Ravi Kumar Pandit
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Malfunctions of Medical Devices Due to Electrostatic Occurrences Big Data Analysis of 10 Years of the FDA’s Reports

IEEE Access, 2018
An electrostatic discharge (ESD) event can cause a medical device to fail and pose a threat to patients'safety. This paper presents the data mining analysis of ESD failures in medical devices, over the last ten years, using the U.S.
Mehdi Kohani, Michael Pecht
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Electrolyte Leakage in Cylindrical Lithium-Ion Batteries Subjected to Temperature Cycling

Energies
In transportation and operation, lithium-ion batteries can be exposed to environments where the temperature exceeds 75 °C, compromising seal integrity and leading to electrolyte leakage and safety issues. Standards introduced by regulatory bodies require
Sahithi Maddipatla, Lingxi Kong, Michael Pecht   +2 more
doaj   +1 more source