Results 71 to 80 of about 1,426,333 (294)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Renewable energy potential of rice straw and paunch manure as bioethanol feedstocks in Central Java, Indonesia

Case Studies in Chemical and Environmental Engineering
Almost all farmers are unaware that rice straw and paunch manure are potential feedstocks for bioethanol besides organic fertilizer, biochar, and biogas.
Forita Dyah Arianti, Joko Triastono, Miranti Dian Pertiwi, Agung Prabowo, Teguh Prasetyo, Chanifah, Bambang Haryanto, Megawati, Widi Astuti, Ira Nurhayati Djarot, Arif Dwi Santoso, Sri Peni Wijayanti   +11 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Buffalo rumen microbial cellulase as a candidate enzyme for hydrolysis of rice straw into glucose: A preliminary study

Open Veterinary Journal
Background: The buffalo rumen microbiome is enriched in functional genes, notably those encoding betaglucosidase which participate in polysaccharide breakdown.
Agung Prabowo, Slamet Hartanto, Dini Dwi Ludfiani, Bambang Haryanto, Miranti Dian Pertiwi, Abd. Azis Wasil, Maya Larasati Donna Wardani, Nandari Dyah Suretno, Rini Nur Hayati, Forita Dyah Arianti, Arif Dwi Santoso, Megawati Megawati, Widi Astuti, Nuruliarizki Shinta Pandupuspitasari, Asih Kurniawati, Zaenal Bachruddin   +15 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Review on Life Cycle Assessment of Solar Photovoltaic Panels

Energies, 2020
The photovoltaic (PV) sector has undergone both major expansion and evolution over the last decades, and currently, the technologies already marketed or still in the laboratory/research phase are numerous and very different.
Vincenzo Muteri, M. Cellura, D. Curto, V. Franzitta, S. Longo, M. Mistretta, M. Parisi   +6 more
semanticscholar   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Ensiling treatment of rice straw with cow paunch content to enhance bioethanol production

Case Studies in Chemical and Environmental Engineering
Every year, the production of rice straw and cow paunch content is abundant and 80 % of them has not been utilized. This study aimed to determine the potency of ensiling treatment on them in producing bioethanol.
Dini Dwi Ludfiani, Forita Dyah Arianti, Miranti Dian Pertiwi, Teguh Prasetyo, Ira Nurhayati Djarot, Arif Dwi Santoso, Nugroho Adi Sasongko, Widi Astuti   +7 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source