Results 111 to 120 of about 908,324 (360)

Housing tenure and wealth distribution in life-cycle economies [PDF]

Common practice in the housing and wealth distribution literature has proceeded as if the modeling of housing rental markets was unnecessary due to renters’ relative low levels of wealth and the small fraction they represent in the total population. This
Pedro Silos
core  

Прогнозування розвитку пошкодженості деталей транспортних систем в задачах судової експертизи з використанням дискретних математичних моделей [PDF]

, 2017
In work on the basis of the cellular automata approach, a technique is proposed for modeling the life cycle of assemblies of rolling stock parts, taking into account internal structural changes in the material.
Кузін, М. О., Лучко, Йосип Йосипович   +1 more
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Frameworks for the application of machine learning in life cycle assessment for process modeling

Cleaner Environmental Systems
In the face of escalating emission reduction demands and heightened public awareness, the imperative for transparent assessments is fundamental to responsible and sustainable development.
Nicolás Martínez-Ramón, Fernando Calvo-Rodríguez, Diego Iribarren, Javier Dufour   +3 more
doaj   +1 more source

Modeling the Effect of Fast Charge Scenario on the Cycle Life of a Lithium-Ion Battery [PDF]

, 2018
Boram Koo, Jaeshin Yi, Dongcheul Lee, Chee Burm Shin, Seongyong Park   +4 more
openalex   +1 more source

Some effects of thermal-cycle-induced deformation in rocket thrust chambers [PDF]

The deformation process observed in the hot gas side wall of rocket combustion chambers was investigaged for three different liner materials. Five thrust chambers were cycled to failure by using hydrogen and oxygen as propellants at a chamber pressure of
Hannum, N. P., Price, R. G., Jr.
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Aerothermal modeling. Executive summary [PDF]

One of the significant ways in which the performance level of aircraft turbine engines has been improved is by the use of advanced materials and cooling concepts that allow a significant increase in turbine inlet temperature level, with attendant ...
Burrus, D. L., Correa, S. M., Kenworthy, M. K.   +2 more
core   +1 more source