Results 101 to 110 of about 174,427 (313)

Life cycle assessment of Libyan crude oil

open access: yes, 2014
Petroleum products such as petrol and diesel are fossil fuels and have a high environmental impact. There is a demand to minimize these impacts especially in the upstream and midstream oil operations, i.e. exploration, production and refining processes,
Irhoma, A, Higginson, M, Su, D
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

The Age-Saving Profile and the Life-Cycle Hypothesis [PDF]

open access: yes
The life-cycle hypothesis posits that saving is positive for young households and negative for the retired, so that wealth should be hump-shaped. Yet, if one looks at the microeconomic evidence on saving by age, dissaving by the elderly is limited or ...
Tullio Jappelli, Franco Modigliani
core  

A probabilistic model for the high cycle fatigue behaviour of cast aluminium alloys subject to complex loads [PDF]

open access: yes, 2013
Lien vers la version éditeur: http://www.sciencedirect.com/science/article/pii/S0142112312002472This article is dedicated to the high cycle fatigue behaviour of cast hypo-eutectic Al–Si alloys and in particular the AlSi7Cu05Mg03 alloy.
PESSARD, Etienne   +3 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Information Modeling For Whole-Life-Cycle Product Based On Step-Ap Development Method

open access: yes, 2003
The enhancing competition of marketing requires\ud product designers collaboratively develop outputs with\ud high quality in a short lead-time. Concerning whole-lifecycle\ud product development, from analysis of customer\ud requirements, concept design ...
Yarlagadda, Prasad K.   +2 more
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

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