Results 111 to 120 of about 7,129,302 (338)
An integrated approach to cause-of-death analysis: cause-deleted life tables and decompositions of life expectancy [PDF]
This article integrates two methods that analyze the implications of various causes of death for life expectancy. One of the methods attributes changes in life expectancy to various causes of death; the other method examines the effect of removing deaths
Hiram Beltran-Sanchez +2 more
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
On the relationship between period and cohort mortality
Demographic Research, 2005 In this paper I explore the formal relationship between period and cohort mortality, focusing on a comparison of measures of mean lifespan. I consider not only the usual measures (life expectancy at birth for time periods and birth cohorts) but also ...
John R. Wilmoth
doaj
Lifesaving increases life expectancy [PDF]
The notion of repeated minimal repair is analyzed and applied to modeling the lifesaving procedure of organisms. Under certain assumptions the equivalence between demographic lifesaving model and reliability shock model is proved.
Maxim S. Finkelstein
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
BMC Public HealthBackground The data from the WHO showed that life expectancy (LE) and health-adjusted life expectancy (HALE) at global level both increased from 2000 to 2019, while they did not increase at the same rate.
Bo Xiong, Yuxiao Chen, Ning Chen
doaj +1 more source
Long-Run Trends of Human Aging and Longevity [PDF]
Over the last 200 years humans experienced a huge increase of life expectancy. These advances were largely driven by extrinsic improvements of their environment (for example, the available diet, disease prevalence, vaccination, and the state of hygiene ...
Holger Strulik, Sebastian Vollmer
core
Universal Mortality Law, Life Expectancy and Immortality
, 2004 Well protected human and laboratory animal populations with abundant resources are evolutionary unprecedented, and their survival far beyond reproductive age may be a byproduct rather than tool of evolution.
Arantes-Oliveira +24 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Lifetime earnings and life expectancy [PDF]
We estimate remaining life expectancy at age 65 using a very large sample of male German pensioners. Our analysis is entirely nonparametric. Furthermore, the data enable us to compare life expectancy in eastern and western Germany conditional on a ...
Hans-Martin von Gaudecker +1 more
core +3 more sources