Results 111 to 120 of about 8,033,101 (355)

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Science in the city region: establishing Liverpool’s life science ecology

open access: yesRegional Studies, Regional Science, 2016
This article focuses on the development of soft and hard infrastructures to support a life science ecology in a peripheral European city region. Liverpool City Region has received almost £1.7bn in capital investment through the EU Cohesion Policy to ...
Dane Anderton
doaj   +1 more source

(Life) Science Funding in Switzerland (1)§

open access: yesCHIMIA, 2016
The Swiss National Science Foundation (SNSF), under mandate from the federal government, supports the high level of science research in Switzerland by funding scientific projects and scientists' careers across all disciplines.
Ayşim Yılmaz
doaj   +1 more source

Ambiguous Bodies, Biopower and the Ideologies of Science Fiction [PDF]

open access: yes, 2016
Contemporary Hollywood film narrates the fear of monstrous science; attending to the modulations of medicine, capital and the body. The filmic body is employed to illustrate the power of the new biotechnologies to create and sustain life and the new ...
Flynn, Susan
core  

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

open access: yesFEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

Microgravity Particle Research on the Space Station [PDF]

open access: yes
Science questions that could be addressed by a Space Station Microgravity Particle Research Facility for studying small suspended particles were discussed. Characteristics of such a facility were determined.
Mckay, Christopher P.   +2 more
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

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