Results 111 to 120 of about 8,207,011 (340)
BioHackathon series in 2011 and 2012: penetration of ontology and linked data in life science domains [PDF]
Toshiaki Katayama +84 more
openalex +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Science in the city region: establishing Liverpool’s life science ecology
This article focuses on the development of soft and hard infrastructures to support a life science ecology in a peripheral European city region. Liverpool City Region has received almost £1.7bn in capital investment through the EU Cohesion Policy to ...
Dane Anderton
doaj +1 more source
(Life) Science Funding in Switzerland (1)§
The Swiss National Science Foundation (SNSF), under mandate from the federal government, supports the high level of science research in Switzerland by funding scientific projects and scientists' careers across all disciplines.
Ayşim Yılmaz
doaj +1 more source
Ripping yarns: Science in Asia [PDF]
The article explores the life and works of botanist Joseph Rock, historian Joseph Needham, and physicist J. C. Bose. Rock's expeditions and personality have become an enduring part of China's history which shows the notion that scientists participate in ...
Barker, Miles
core +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
The LAILAPS Search Engine: A Feature Model for Relevance Ranking in Life Science Databases [PDF]
Matthias Lange +5 more
openalex +1 more source
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source

