Results 101 to 110 of about 398,606 (255)
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Lifespan development: a social-cultural perspective [PDF]
, 2006 This thesis explores some of the social factors that may affect individuals as they age. A lifespan developmental perspective is employed in investigating the effects of societal aging stereotypes on will-to-live and risk-taking skills.
Ashman, Ori
core
Considering generations from a lifespan developmental perspective
, 2017 We extend recent critiques of research on generations in the work context by proposing a differentiated lifespan developmental perspective. We accomplish this through several means: First, we define generations and trace the historical development of ...
Rudolph, Cort W., Zacher, Hannes
core +1 more source
Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone +8 more
wiley +1 more source
Generalization from early to middle childhood
Scientific ReportsGeneralization enables individuals to apply knowledge derived from past experiences in novel situations, yet it is unclear whether common experimental paradigms probe the same underlying ability in early to middle childhood.
Tydings M. McClary +6 more
doaj +1 more source
Reframing brain aging: neuroinflammation as an interconnected network process
Frontiers in AgingNeuroinflammation has emerged as a central component of brain aging, shaping the balance between neural resilience and vulnerability to cognitive decline.
Ludmila Müller +2 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak +4 more
wiley +1 more source
Risk factors of multimorbidity among older adults in India: A systematic review and meta‐analysis
Health Science ReportsBackground Multimorbidity among older adults is a growing concern in India. Multimorbidity is defined as the coexistence of two or more chronic health conditions in an individual.
Nikita Goel +2 more
doaj +1 more source
Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky +5 more
wiley +1 more source