Results 111 to 120 of about 398,606 (255)

Establishing a role for specific nutrients in Drosophila dietary restriction [PDF]

open access: yes, 2009
Dietary restriction (DR), the reduction in food intake that falls short of starvation, has been shown to be the most robust and reproducible intervention to extend lifespan in diverse organisms ranging from yeast to mammals, including the fruit fly ...
Grandison, R.
core  

Ayurveda for Managing Noncommunicable Diseases in Organisation for Economic Cooperation and Development Nations: A Qualitative Systematic Review

open access: yesHealth Science Reports
Background Ayurveda, a traditional system of medicine, has gained recognition in the Organisation for Economic Cooperation and Development (OECD) countries as a complementary and alternative medicine for managing noncommunicable diseases (NCDs ...
Patricia Egwumba   +4 more
doaj   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram   +3 more
wiley   +1 more source

Reserves, Injury Severity, and Outcomes in Traumatic Brain Injury: A CENTER‐TBI Observational Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Reserve refers to the brain's ability to maintain function after an injury and strongly relates to traumatic brain injury (TBI) outcomes. This study examined (1) whether associations between pre‐injury reserve proxies and outcomes differed across injury severity categories, and (2) whether the impact of injury severity varied across ...
Natascha Ekdahl   +6 more
wiley   +1 more source

PrimeTimes Newsletter, Fall 2015 [PDF]

open access: yes, 2015
PrimeTimes is the newsletter of the Office of Lifespan Studies in the College of Science at Coastal Carolina ...
Office of Lifespan Studies
core  

Fecundity and lifespan manipulations in Caenorhabditis elegans using exogenous peptides

open access: yes, 2008
In this study using Caenorhabditis elegans, we have been able to suppress (>60%) and enhance (>40%) fecundity (number of offspring) while extending lifespan by a fifth, by administering synthetic peptides to the aqueous medium in ...
Keith G. Davies   +3 more
core   +1 more source

Neurological, Neurodevelopmental and Treatment Outcomes in Patients With Pyruvate Dehydrogenase Complex Deficiency

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of this study was to characterize intellectual and motor function, neurological features including epilepsy, treatment response, and adaptive behavior in patients with pyruvate dehydrogenase complex deficiency (PDCD) in Sweden.
Antri Savvidou   +6 more
wiley   +1 more source

PrimeTimes Newsletter, Winter 2006-2007 [PDF]

open access: yes, 2006
PrimeTimes is the newsletter of the Office of Lifespan Studies in the College of Science at Coastal Carolina ...
Office of Lifespan Studies
core  

microRNA‐7‐5p and α‐Synuclein SAA Predict Parkinson's Disease Phenoconversion

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corroborate blood neuron‐derived extracellular vesicle (NDEV) alpha‐synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn‐SAA), and blood microRNA‐7‐5p (miR‐7‐5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be more likely to phenoconvert.
Shayan Zadegan   +4 more
wiley   +1 more source

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