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Lifespan Changes of the Human Brain In Alzheimer’s Disease [PDF]

open access: yesScientific Reports, 2019
AbstractBrain imaging studies have shown that slow and progressive cerebral atrophy characterized the development of Alzheimer’s Disease (AD). Despite a large number of studies dedicated to AD, key questions about the lifespan evolution of AD biomarkers remain open. When does the AD model diverge from the normal aging model?
Coupé, Pierrick   +3 more
openaire   +5 more sources

Perturbing the community grammar: Individual differences and community-level constraints on sociolinguistic variation

open access: yesGlossa, 2019
The traditional focus of variationist sociolinguistic research is the patterning of language variation at the level of the community, which individual language users are said to learn and reproduce (Labov 1972; 2012).
Laurel MacKenzie
doaj   +2 more sources

Decadal-centennial scale monsoon variations in the Arabian Sea during the Early Holocene [PDF]

open access: yes, 2002
An essential prerequisite for the prediction of future climate change due to anthropogenic input is an understanding of the natural processes that control Earth's climate on timescales comparable to human-lifespan. The Early Holocene period was chosen to
Anderson   +26 more
core   +1 more source

Brain Dynamics Underlying Cognitive Flexibility Across the Lifespan.

open access: yesCerebral Cortex, 2021
The neural mechanisms contributing to flexible cognition and behavior and how they change with development and aging are incompletely understood. The current study explored intrinsic brain dynamics across the lifespan using resting-state fMRI data (n ...
Lauren Kupis   +10 more
semanticscholar   +1 more source

Editorial

open access: yesLifespans and Styles, 2017
It is my pleasure to present the first issue of the third volume of Lifespans & Styles: Undergraduate Working Papers on Intraspeaker Variation . This issue includes five papers on topics about within-speaker variation that are largely under-researched in
Lauren Hall-Lew
doaj   +1 more source

The Crucial Roles of Phospholipids in Aging and Lifespan Regulation

open access: yesFrontiers in Physiology, 2021
Phospholipids are major membrane lipids that consist of lipid bilayers. This basic cellular structure acts as a barrier to protect the cell against various environmental insults and more importantly, enables multiple cellular processes to occur in ...
Yucan Dai, Haiqing Tang, Shanshan Pang
semanticscholar   +1 more source

Does Geographic Relocation Induce the Loss of Features from a Single Speaker’s Native Dialect?

open access: yesLifespans and Styles, 2016
Over the past few years, academics such as Sankoff and Blondeau (2007) and Harrington (2006) have exhibited a marked interest in dialect variation and language change across the lifespan.
Hollie Barker
doaj   +1 more source

Demographic Change Across the Lifespan of Pet Dogs and Their Impact on Health Status

open access: yesFrontiers in Veterinary Science, 2018
Although dogs' life expectancies are six to twelve times shorter than that of humans, the demographics (e. g., living conditions) of dogs can still change considerably with aging, similarly to humans.
L. Wallis   +3 more
semanticscholar   +1 more source

Sixty Years of Speech: A Study of Language Change in Adulthood

open access: yesLifespans and Styles, 2016
Research on language change has been complicated and hindered by the problem of obtaining quality data. In many cases, the large volume of time required to collect recorded speech at different intervals, as necessary in lifespan studies, is prohibitive ...
Bei Qing Cham
doaj   +1 more source

Aging in vitro and D-glucose uptake kinetics of diploid human fibroblasts [PDF]

open access: yes, 1981
By use of a rapid technique, initial rates of D-glucose transport were obtained during the lifespan in vitro of a commercially available strain of human embryo lung fibroblasts (Flow 2000).
Aizawa   +38 more
core   +1 more source

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