Results 41 to 50 of about 80,393 (300)
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Two Approaches to the Problem of High-cycle Fatigue of Materials and Structures
Creation of new types of materials and development of new methods aimed at extending the lifetime of structures are two interconnected approaches to solve the problem of metallic structures fatigue.
Mironov Vladimir +2 more
doaj +1 more source
Calculation of low-energy-electron lifetimes [PDF]
Peer ...
Zarate, E. +2 more
openaire +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Effective lifetime of minority carriers in black silicon nano-textured by cones and pyramids
We calculated the dependence of effective lifetime of minority carriers in black silicon nano-textured by cones and pyramids on the diameter of the cone base, the side of the pyramid base, the height of cone and pyramid.
V.F. Onyshchenko +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diffusion Simulation and Lifetime Calculation at RHIC [PDF]
The beam lifetime is an important parameter for any storage ring. For protons in RHIC it is dominated by the non-linear nature of the head-on collisions that causes the particles to diffuse outside the stable area in phase space. In this report we show results from diffusion simulation and lifetime calculation for the 2006 and 2008 polarized proton ...
Abreu, N.P. +3 more
openaire +4 more sources
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Positron lifetime calculations for defects in Zn
The effect of the lattice relaxation at vacancy clusters and interstitial-type dislocation loops on the lifetime of positrons in Zn has been studied. Defective relaxed structures have been generated for the lifetime calculations by using a many-body potential for Zn.
Campillo-Robles, Jose Miguel +2 more
openaire +3 more sources

