Results 61 to 70 of about 80,743 (300)
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
The extended Touschek lifetime [PDF]
, 1996 With the advent of synchrotron radiation sources, the issue of beam lifetime becomes increasingly important. Users of these machines need to perform experiments which seldom last 15 minutes, but require hours for their completion.
Bizek, H.M., Bizek, H. M.
core +1 more source
Applied SciencesThis paper presents theoretical notions with practical applications for establishing the lifetime of a dental bur (durability and reliability) based on the wear of the active part and considering a series of statistical indicators.
Filip Ilie
doaj +1 more source
CALCULATION OF RESIDUAL LIFETIME FOR LIFTING INSTALATION – GANTRY CRANE MPT 20/5 [PDF]
Fiabilitate şi Durabilitate, 2013 In this paper is presented step-by-step the calculus made in order to establishing the residuallifetime of a lifting crane using also non-destructive methods to establish the actual state of machine andareas subject to study, conducting to an extension ...
Cătălin IANCU, Florin VÎLCEANU
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Journal of High Energy Physics, 2020 We complete the calculation of the contributions from the dimension six operators in the heavy quark expansion for the total lifetime of heavy hadrons. We give the leading order expressions for the Wilson coefficients of the Darwin term ρ D and the spin ...
Th. Mannel, D. Moreno, A. A. Pivovarov
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
机车电传动, 2019 IGBT module is the core component of the train traction converter, its life prediction technology is an important basis for the prognostic and health management of the whole train.
Lin CAO +5 more
doaj
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source