Results 111 to 120 of about 1,008,319 (276)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

RESEARCH ON THE AERODYNAMICS OF BLADE PROFILES OF WIND TURBINES [PDF]

open access: yesJournal of Sustainable Energy, 2016
Small capacity wind turbine performance is influenced in a large extent by the blade profiles aerodynamics. By this point of view, the paper presents the most important aspects of aerodynamic profiles, and aspects concerning their optimization in ...
POP E.S., CAMPEAN E., DRAGAN T.
doaj  

Experimental and analytical study of the longitudinal aerodynamic characteristics of analytically and empirically designed Strake-wing configurations at subcritical speeds [PDF]

open access: yes
Sixteen analytically and empirically designed strakes have been tested experimentally on a wing-body at three subcritical speeds in such a way as to isolate the strake-forebody loads from the wing-afterbody loads.
Frink, N. T., Lamar, J. E.
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Two-dimensional wind-tunnel tests of a NASA supercritical airfoil with various high-lift systems. Volume 1: Data analysis [PDF]

open access: yes
High-lift systems for a NASA, 9.3%, method for calculating the viscous flow about two-dimensional multicomponent airfoils was evaluated by comparing its predictions with test data.
Mahal, A., Omar, E., Zierten, T.
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

OPTIMASI FOIL NACA 63(3)018 PADA KAPAL HIDROFOIL MENGGUNAKAN PARTICLE SWARM (PSO)

open access: yesTeknika: Engineering and Sains Journal, 2018
Hidrofoil adalah sebuah kapal dengan bagian seperti sayap yang dipasang pada penyangga di bawah lambung kapal. Ketika kapal meningkatkan kecepatannya, hidrofoil memproduksi gaya angkat sehingga lambungnya terangkat dan keluar dari air.
Eva Hertnacahyani Herraprastanti   +2 more
doaj  

New probabilistic interest measures for association rules

open access: yes, 2008
Mining association rules is an important technique for discovering meaningful patterns in transaction databases. Many different measures of interestingness have been proposed for association rules.
Hahsler, Michael, Hornik, Kurt
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

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