Results 151 to 160 of about 237,722 (291)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

In-Car Noise Computation for a High-Rise Lift

, 2017
The authors have developed an acoustic model of a lift, using a multi-disciplinary approach. The model enables a full understanding of how the lift design is affected by noise requirements inside the car, and in buildings that are still in planning or ...
Tanttari, Jukka; id_orcid, Kalliomäki, Jaakko, Lehtinen, Antti, Roivainen, Gabriela   +3 more
core  

Lift-Sharing for Travel to and from Children’s Activities: survey questions

The item contains the survey questions to assess the current prevalence of lift-sharing (for children’s activities and other types of trips) in families with young children, the factors influencing its uptake, the experiences and attitudes of regular ...
Marcus Enoch (1171632), Sarah-Anne De-Kremer (1249275), Tracy Ross (1249074), Fredrik Monsuur (6815885)   +3 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

I will lift up mine eyes: sacred song

, 1919
I will lift up mine eyes to the hillsDedicated to Mrs. B.

core   +1 more source

Effects of emphasized plantarflexion stop and heel lift height on the plantarflexion resistive torque in healthy young adults wearing ankle foot orthoses. [PDF]

J Phys Ther Sci
Fujimoto M, Suzuki S, Masuda M, Kuki H.
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Analysing ‘lift-off’ events during knee wear testing

, 2010
The lower conformity and bi-condylar nature of the knee makes condylar ‘lift-off’ (LO) an issue; fluoroscopy studies show condylar LO in many cases[1].
Taylor, Mark, Strickland, Michael A.
core  

Graft-Free Sinus Lift Using a Resorbable Magnesium Membrane vs. Standard Grafting Protocol: A Bilateral Case Report with Histological Evaluation. [PDF]

Dent J (Basel)
Scognamiglio C, Perucchi A, Čandrlić M, Perić Kačarević Ž.   +3 more
europepmc   +1 more source