Results 81 to 90 of about 237,722 (291)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Experimental study of the aerodynamics of micro airfoils with wavy surface and the use of different patterns inspired by nature [PDF]
فناوری در مهندسی هوافضاEnhancing the aerodynamic performance of airfoils, minimizing drag, and controlling flow separation are key objectives in aerospace research, pursued through various methods.
Mehdi Abedi, Ramin Zakeri
doaj +1 more source
computational complexityAbstract Lifting theorems are used to transfer lower bounds between Boolean function complexity measures. Given a lower bound on a complexity measure $$A$$ A
Alekseev, Yaroslav +2 more
openaire +4 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Examination of three candidate technologies for high-lift devices on an aircraft wing [PDF]
, 2005 A research programme was initiated to examine three candidate high-lift technologies, which would, if implemented, simplify the mechanical complexity of the multiple component trailing-edge devices traditionally employed on civil transport aircraft ...
Knepper, Angela Marie
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Improved Design for Horizontal Axis Wind Turbine Blades with Winglets
Platform, a Journal of Engineering, 2023 The horizontal axis wind turbine blades are modified to enhance the turbine's aerodynamic performance. The performance of the modified geometry was evaluated by comparing the lift, drag and torque findings to the same propeller with a
Hamza Ben Ahmadi +5 more
doaj
Proceedings, 2018 The present study studied the flow boiling heat transfer performance of a mini channel with offset fins experimentally. The hydraulic diameter for it is 1.59 mm with 9 offset rectangular channels. The influences of saturation pressure, mass flux and heat
Tao Wen +3 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source