Results 251 to 260 of about 379,006 (309)
Dinitrosyl iron complexes with thiolate ligands: Physico-chemistry, biochemistry and physiology
Some present-day concepts on the origin and functional activities of dinitrosyl iron complexes (DNIC) with thiolate ligands are considered. Nitric oxide (NO) including to DNIC increases its stability and ensures effective targeting of NO to organs and tissues.
А. Ф. Ванин
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The experiment described here uses the binding of cyanine dyes to DNA as a model system for demonstrating the role that both ligand structure and noncovalent interactions play in DNA binding. Upper-division biochemistry laboratory students observe changes in absorbance and fluorescence spectra when small molecules bind either in the minor groove of DNA
Kristen C. Roy
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2-Arachidonoylglycerol (2-AG) is a unique molecular species of monoacylglycerol isolated in 1995 from rat brain and canine gut as an endogenous ligand for the cannabinoid receptors. 2-AG is rapidly formed from arachidonic acid-containing phospholipids through increased phospholipid metabolism, such as enhanced inositol phospholipid turnover, in various
Takayuki, Sugiura +3 more
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The interaction between oxygen and hemoglobin is a classic example of a cooperative ligand-binding process. This gaseous-ligand binding process may be studied in the undergraduate laboratory with a variable-pressure cuvette apparatus. An updated method is described to assemble a variable-pressure cuvette apparatus composed of inexpensive supplies and ...
Megan K. M. Young, Theodore J. Gries
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The similarity in the functional spectra of many endogenous regulatory oligopeptides [1] allows the assumption that these molecules possess some common physicochemical properties. These properties provide the basis for the interaction of an oligopeptide with a particular set of receptor structures, and this interaction is the initial step of the ...
A. A. Zamyatnin, O. L. Voronina
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AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
N. V. BOVIN, H.‐J. GABIUS
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We have developed an experiment that utilizes the salt dependence of spermine binding to DNA as a means to introduce experimental design concepts and polyelectrolyte effects in the undergraduate biochemistry lab. The experiment is easily completed in two, three-hour lab periods.
Matthew A. Fisher +2 more
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Histamine Receptors: Specific Ligands, Receptor Biochemistry, and Signal Transduction
During the past few years, there has been a tremendous increase in our understanding of the histamine receptors. Important progress has been made in the development of H1-receptor agonists and the rationalization of H1-receptor-ligand interaction. The recent observation of constitutive H1- and H2-receptor activity has led to a reclassification of H1 ...
Remko A. Bakker, H. Timmerman, Rob Leurs
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Equilibrium gel filtration liquid chromatography is a technique used for the quantitation of ligand binding. We have designed an experiment for the senior undergraduate laboratory using this technique for the measurement of the binding of ATP to cytochrome c.
Douglas B. Craig
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