Results 251 to 260 of about 363,417 (316)

Future Frontiers in Bioinspired Implanted Biomaterials

Advanced Materials, EarlyView.
Gu et al. present an integrative overview of cutting‐edge strategies in bioinspired implantable biomaterials for organ regeneration, highlighting how emerging approaches—including 3D bioprinting, scaffold design, hydrogel systems, surface modification, nanofiber engineering, and genetic manipulation—converge to restore structure and function across ...
Qi Gu, Rui Yuan, Dadi Sun, Gordon Wallace   +3 more
wiley   +1 more source

Edge-enhanced interaction graph network for protein-ligand binding affinity prediction. [PDF]

PLoS One
Yang D, Kuang L, Hu A.
europepmc   +1 more source

Biomimetic Cell Membrane‐Coated Scaffolds for Enhanced Tissue Regeneration

Advanced Materials, EarlyView.
This review examines the development and use of cell membrane‐coated scaffolds in tissue engineering. Bioinspired phospholipid and glycocalyx coatings enhance anti‐fouling, anti‐thrombogenic, and selective molecular recognition properties. Native cell membrane coatings further support cell‐specific interactions, immune modulation, and reduced bacterial
Carmen Alvarez‐Lorenzo, Alejandro Ramirez‐Romero, Diana Peixoto, Maria Vivero‐Lopez, Isabel Rodríguez‐Moldes, Angel Concheiro   +5 more
wiley   +1 more source

Computational investigation unveils pathogenic LIG3 non-synonymous mutations and therapeutic targets in acute myeloid leukemia. [PDF]

PLoS One
Hossen MA, Jahan UMS, Hossain MA, Asif KH, Rahman A, Ahmed S, Uddin MM, Amin MF, Barik MA, Islam MJ, Kamruzzaman M, Hasnat S, Uddin MN, Islam T, Hoque MN.   +14 more
europepmc   +1 more source

Mechanoresponsive Hydrogels Emerging from Dynamic and Non‐Covalent Interactions

Advanced Materials, EarlyView.
Mechanoresponsive behaviors in hydrogels often arise from dynamic or non‐covalent interactions between polymer chains. This review highlights self‐healing, shear‐thinning, shear‐thickening, and strain‐stiffening hydrogels formed through dynamic crosslinking motifs, discussing their underlying mechanisms and emergent applications across biomedical and ...
Rachel C. Ollier, Matthew J. Webber
wiley   +1 more source

Human Milk Oligosaccharides Multivalently Presented on Defined Synthetic Neo-Glycoproteins Are Nanomolar Ligands of Tandem-Repeat Galectins. [PDF]

Biomacromolecules
Červený J, Heine V, Hovorková M, Brož P, Filipová E, Kulik N, Hubálek M, Cvačka J, Petrásková L, Florencio-Zabaleta M, Delgado S, Pelantová H, Bosáková Z, Elling L, Jiménez-Barbero J, Ardá A, Křen V, Bojarová P.   +17 more
europepmc   +1 more source

Reengineering Endogenous Targeting Lipid Nanoparticles (ENDO) for Systemic Delivery of mRNA to Pancreas

Advanced Materials, EarlyView.
ENDO lipid nanoparticles containing cholecalciferol as a fifth component demonstrate mRNA delivery to the pancreas with 99% selectivity, including beta cells. This platform shows minimal toxicity and sustained protein expression for up to 3 days in a dose‐dependent manner, offering a novel approach to pancreas‐specific mRNA delivery and gene therapy ...
Ivan Isaac, Luv Patel, Nguyen Tran, Amarnath Singam, DongSoo Yun, Prasun Guha, Seungman Park, Chandrabali Bhattacharya   +7 more
wiley   +1 more source

Aldo-keto reductase family 1 member C3 (AKR1C3) gene polymorphism (rs12529) is associated with breast cancer in Bangladeshi population: A case-control study and computational investigation. [PDF]

PLoS One
Shaon MA, Ansari F, Mahmud Z, Tamanna S, Ibrahim MNB, Alam NF, Hossain MN, Howlader MZH.   +7 more
europepmc   +1 more source

Zinc‐Coordinated Trienzyme Nanogel Cascade Therapy for Accelerated Post‐Pancreatectomy Cutaneous Wound Healing

Advanced Materials, EarlyView.
A zinc‐coordinated nanogel assembly is reported that co‐delivers three enzymes to regulate glucose, oxidative stress, and oxygen levels. This system mimics natural enzyme cascades to reprogram the wound environment after pancreatectomy. In a post‐pancreatectomy mouse model, it accelerates healing by reducing infection, promoting blood vessel growth ...
Yedong Ma, Chengke Xie, Chengyu Liao, Binting Huang, Siqi Liu, Junhua Kong, Xiaotong Fan, Zibiao Li, Shi Chen, Chaobin He   +9 more
wiley   +1 more source

One-step functionalization of gold nanorods with N-heterocyclic carbene ligands. [PDF]

RSC Adv
Dominique NL, Nalaoh P, Jenkins DM, Vaia R, Park K, Camden JP.   +5 more
europepmc   +1 more source