Results 271 to 280 of about 363,417 (316)
The similarity in the functional spectra of many endogenous regulatory oligopeptides [1] allows the assumption that these molecules possess some common physicochemical properties. These properties provide the basis for the interaction of an oligopeptide with a particular set of receptor structures, and this interaction is the initial step of the ...
Andrey A. Zamyatnin, Olga L. Voronina
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N-Allyl-, N-(cyclopropylmethyl)-, and N-propyl-endo-ethenotetrahydronororipavines (N-substituted 6,14-endo-etheno-4,5-epoxy-3-hydroxy-6-methoxymorphinans) were synthesized with potential acylating or alkylating moieties at the C-7 position (isothiocyanato, (bromoacetyl)amino, and (methoxyfumaroyl)amino) and examined in vivo for their narcotic agonist ...
Ralph A. Lessor+9 more
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Equilibrium gel filtration liquid chromatography is a technique used for the quantitation of ligand binding. We have designed an experiment for the senior undergraduate laboratory using this technique for the measurement of the binding of ATP to cytochrome c.
Douglas B. Craig
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AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Nicolai V. Bovin, Hans‐Joachim Gabius
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AbstractThe presence of Fe‐bound cyanide ligands in the active site of the proton‐reducing enzymes [FeFe]‐hydrogenases has led to the hypothesis that such Brønsted–Lowry bases could be protonated during the catalytic cycle, thus implying that hydrogen isocyanide (HNC) might have a relevant role in such crucial microbial metabolic paths.
Claudio Greco+4 more
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The experiment described here uses the binding of cyanine dyes to DNA as a model system for demonstrating the role that both ligand structure and noncovalent interactions play in DNA binding. Upper-division biochemistry laboratory students observe changes in absorbance and fluorescence spectra when small molecules bind either in the minor groove of DNA
Kristen C. Roy
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The interaction between oxygen and hemoglobin is a classic example of a cooperative ligand-binding process. This gaseous-ligand binding process may be studied in the undergraduate laboratory with a variable-pressure cuvette apparatus. An updated method is described to assemble a variable-pressure cuvette apparatus composed of inexpensive supplies and ...
Megan K. M. Young, Theodore J. Gries
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Metal-Ligand Interactions in Organic Chemistry and Biochemistry
Bernard Pullman, Natan Goldblum
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