Results 31 to 40 of about 1,156,300 (324)

Recent Advances in Optical DNA Biosensors Technology

CHIMIA, 2005
Recent advances in nucleic acids-based biosensors have led to the development of DNA biosensors for DNA hybridisation detection and for nucleic acid–ligand binding studies.
Bambang Kuswandi, Sara Tombelli, Giovanna Marazza, Marco Mascini   +3 more
doaj   +1 more source

Phytosterol, Lipid and Phenolic Composition, and Biological Activities of Guava Seed Oil

Molecules, 2020
Plant seeds have been found to contain bioactive compounds that have potential nutraceutical benefits. Guava seeds (Psidium guajava) are by-products in the beverage and juice industry; however, they can be utilized for a variety of commercial purposes ...
Adchara Prommaban, Niramon Utama-ang, Anan Chaikitwattana, Chairat Uthaipibull, John B. Porter, Somdet Srichairatanakool   +5 more
doaj   +1 more source

Theoretical Evaluation of Novel Thermolysin Inhibitors from Bacillus thermoproteolyticus. Possible Antibacterial Agents

Molecules, 2021
The search for new antibacterial agents that could decrease bacterial resistance is a subject in continuous development. Gram-negative and Gram-positive bacteria possess a group of metalloproteins belonging to the MEROPS peptidase (M4) family, which is ...
Emilio Lamazares, Desmond MacLeod-Carey, Fernando P. Miranda, Karel Mena-Ulecia   +3 more
doaj   +1 more source

Structural and biochemical determinants of ligand binding by the c-di-GMP riboswitch .

Biochemistry, 2010
The bacterial second messenger c-di-GMP is used in many species to control essential processes that allow the organism to adapt to its environment. The c-di-GMP riboswitch (GEMM) is an important downstream target in this signaling pathway and alters gene
Kathryn D. Smith, S. V. Lipchock, Alison L. Livingston, Carly A. Shanahan, S. Strobel   +4 more
semanticscholar   +1 more source

Ligand Modulation of Lateral Segregation of a G-Protein-Coupled Receptor into Lipid Microdomains in Sphingomyelin/Phosphatidylcholine Solid-Supported Bilayers [PDF]

Biochemistry, 2005
A growing body of evidence supports the idea that the plasma membrane bilayer is characterized by a laterally inhomogeneous mixture of lipids, having an organized structure in which lipid molecules segregate into small domains or patches. Such microdomains are characterized by high contents of sphingolipids that form thicker liquid-ordered regions that
Gordon Tollin, Isabel D. Alves, Zdzislaw Salamon, Victor J. Hruby   +3 more
openaire   +5 more sources

4-[(E)-2-(1-Pyrenyl)Vinyl]Pyridine Complexes: How to Modulate the Toxicity of Heavy Metal Ions to Target Microbial Infections

Molecules
Pyrene derivatives are regularly proposed for use in biochemistry as dyes due to their photochemical characteristics. Their antibacterial properties are, however, much less well understood. New complexes based on 4-[(E)-2-(1-pyrenyl)vinyl]pyridine (PyPe)
Justine V. Schwarte, Aurélien Crochet, Katharina M. Fromm   +2 more
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Advances in thiosemicarbazone metal complexes as anti-lung cancer agents

Frontiers in Pharmacology, 2022
The great success of cisplatin as a chemotherapeutic agent considerably increased research efforts in inorganic biochemistry to identify more metallic drugs having the potential of treating lung cancer.
Xian-Guang Bai, Yunyun Zheng, Jinxu Qi
doaj   +1 more source

Ligand interactions and protein conformational changes of phosphopyridoxyl‐labeled Escherichia coli phosphoenolpyruvate carboxykinase determined by fluorescence spectroscopy [PDF]

European Journal of Biochemistry, 2002
Escherichia coli phosphoenolpyruvate (PEP) carboxykinase catalyzes the decarboxylation of oxaloacetate and transfer of the γ‐phosphoryl group of ATP to yield PEP, ADP, and CO2. The interaction of the enzyme with the substrates originates important domain movements in the protein.
Encinas, MV, Gonzalez-Nilo, FD, Goldie, H, Cardemil, E   +3 more
openaire   +5 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source