Results 61 to 70 of about 369,161 (297)

The Biochemical Properties of Manganese in Plants

open access: yesPlants, 2019
Manganese (Mn) is an essential micronutrient with many functional roles in plant metabolism. Manganese acts as an activator and co-factor of hundreds of metalloenzymes in plants.
Sidsel Birkelund Schmidt, Søren Husted
doaj   +1 more source

Evaluation of new antihypertensive drugs designed in silico using Thermolysin as a target

open access: yesSaudi Pharmaceutical Journal, 2020
The search for new therapies for the treatment of Arterial hypertension is a major concern in the scientific community. Here, we employ a computational biochemistry protocol to evaluate the performance of six compounds (Lig783, Lig1022, Lig1392, Lig2177,
Desmond MacLeod-Carey   +3 more
doaj   +1 more source

Molecular Requirements for Ethanol Differential Allosteric Modulation of Ligand-Gated Ion Channels Based on Selective G Beta Gamma Modulation [PDF]

open access: yes, 2010
It is now believed that the allosteric modulation produced by ethanol in glycine receptors (GlyRs) depends on alcohol binding to discrete sites within the protein structure.
Aguayo, Luis G   +6 more
core   +1 more source

Establishing the entatic state in folding metallated Pseudomonas aeruginosa azurin [PDF]

open access: yes, 2007
Understanding how the folding of proteins establishes their functional characteristics at the molecular level challenges both theorists and experimentalists.
Adman   +25 more
core   +3 more sources

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Extracellular vesicles (EVs) mediate intercellular communication in tumor immune microenvironments. However, their role in B‐cell malignancies remains poorly defined, owing to biological complexity and technical challenges in EV isolation and analysis.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

Factors affecting light energy transfer in some samarium complexes

open access: yesInternational Journal of Photoenergy, 2005
The photophysical properties of samarium ion in presence of 7-Acetoxy Coumarin 3-Carboxylic acid (ACC) or 1-(4-methoxyphenyl) 3-(4-t-butyl phenyl) 1,3-propandione (MBPK), which act as antenna of near-UV radiation, are studied in different homogeneous ...
Esam Bakier, M. S. A. Abdel-Mottaleb
doaj   +1 more source

Current Views on the Roles of O-Glycosylation in Controlling Notch-Ligand Interactions

open access: yesBiomolecules, 2021
The 100th anniversary of Notch discovery in Drosophila has recently passed. The Notch is evolutionarily conserved from Drosophila to humans. The discovery of human-specific Notch genes has led to a better understanding of Notch signaling in development ...
Wataru Saiki   +3 more
doaj   +1 more source

Origin of life: β‐sheet amyloid conformers as the primordial functional polymers on the early Earth and their role in the emergence of complex dynamic networks

open access: yesFEBS Letters, EarlyView.
The amyloid world hypothesis of the origin‐of‐life posits that the first functional polymers on the early Earth were structurally stable cross‐β‐sheet‐based peptide amyloids capable of Darwinian‐like evolution. Peptide amyloids display self‐replication and information transfer, as well as catalytic, adaptive, and evolutive properties.
Carl Peter J. Maury
wiley   +1 more source

Serum Mediators in Patients with Both Type 2 Diabetes Mellitus and Pruritus

open access: yesActa Dermato-Venereologica, 2023
Chronic pruritus is an unpleasant sensory perception that negatively affects quality of life and is common among patients with type 2 diabetes mellitus. Current antipruritic therapies are insufficiently effective. Thus, the mediation of diabetic pruritus
Guan-Yi He   +6 more
doaj   +1 more source

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