Results 151 to 160 of about 1,596,891 (346)

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Photodynamic killing of cancer cells by a Platinum(II) complex with cyclometallating ligand [PDF]

open access: gold, 2016
Rachel Doherty   +8 more
openalex   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Humic substances influence on the distribution of dissolved iron in seawater: A review of electrochemical methods and other techniques

open access: yesOpen Geosciences
Iron (Fe) is an essential trace element for the growth of phytoplankton in the ocean. Humic substances (HSs) are key components of dissolved Fe-binding organic ligands (Lt).
Su Han
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Cu66 nanoclusters from hierarchical square motifs: Synthesis, assembly, and catalysis

open access: yesAggregate
The elucidation of hierarchical assembly structure of metal nanoclusters is of fundamental importance in the context of bottom‐up fabrication and functionalization.
Xueli Sun   +8 more
doaj   +1 more source

Peer Review #3 of "Image-based effective feature generation for protein structural class and ligand binding prediction (v0.2)"

open access: gold, 2020
Nafees Sadique   +91 more
openalex   +2 more sources

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