Results 71 to 80 of about 905,008 (316)
Ligand‐dependent ribozymes [PDF]
WIREs RNA, 2016 The discovery of catalytic RNA (ribozymes) more than 30 years ago significantly widened the horizon of RNA‐based functions in natural systems. Similarly to the activity of protein enzymes that are often modulated by the presence of an interaction partner, some examples of naturally occurring ribozymes are influenced by ligands that can either act as ...
Felletti, Michele, Hartig, Jörg S.
openaire +3 more sources
Iridium-catalyzed asymmetric hydrogenation of β-keto esters with new phenethylamine-derived tridentate P,N,N-ligands [PDF]
, 2019 A new class of phenethylamine-derived tridentate P,N,N-ligands has been successfully developed. These ligands exhibited good performance in the Ir-catalyzed asymmetric hydrogenation of β-keto esters, affording the corresponding β-hydroxy esters in ...
Xiu-Shuai Chen (3341609) +3 more
core +1 more source
Nuclear Hormone Receptors and Their Ligands: Metabolites in Control of Transcription
Cells, 2020 Nuclear hormone receptors are a family of transcription factors regulated by small molecules derived from the endogenous metabolism or diet. There are forty-eight nuclear hormone receptors in the human genome, twenty of which are still orphans.
Lian Jing Tao +4 more
doaj +1 more source
Crystals, 2022 Understanding DNA–ligand binding interactions requires ligand screening, crystallization, and structure determination. In order to obtain insights into the amyloid peptide precursor (APP) gene–Thioflavin T (ThT) interaction, single crystals of two DNA ...
Hristina Sbirkova-Dimitrova +5 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Ambidentate ligands : the preparation and study of phosphine crown systems [PDF]
, 1987 The aza crown, sym-1,2-benzo-aza-17-crown-5, was synthesized from 6-aza-3,9-dioxa-1,11-undecanediol, and , -dibromo-o-xylene in the presence of potassium tert-butoxide. This new crown ether was reacted with 4-bromobenzyl bromide and chloroacetyl chloride
Farazi, Vida
core
Amphiphilic Biaryl Monophosphine Ligands by Regioselective Sulfonation [PDF]
, 2020 Amphiphilic ligands are valued for their ability to facilitate organometallic reactions in the presence of water. The regioselective sulfonation of a series of commercially available biaryl monophosphines to generate amphiphilic ligands is presented ...
Jacob, Rodriguez +2 more
core +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Asymmetric ligands for lanthanide(II) reagents [PDF]
, 1999 Although the use of Ln(^2+) species as one electron reducing agents has recently become popular, relatively few processes have focused on the control of stereochemistry by the incorporation of chiral auxiliaries at the metal centre. This thesis discusses
Dent, Phillip Damian
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