Synthesis and characterization of gold(I) complexes of dibenzotropylidene-functionalized NHC ligands (Trop-NHCs) [PDF]
, 2015 The ERC (Advanced Investigator Award-FUNCAT), Syngenta, and the EPSRC are gratefully thanked for support of this work. S.P.N. is a Royal Society Wolfson Research Merit Award holder.Gold(I) complexes of dibenzotropylidene-functionalized N-heterocyclic ...
Slawin, Alexandra MZ +17 more
core +1 more source
Eclética QuímicaThe use of medicinal plants as an alternative mean of treating various diseases has drawn the attention of several researchers. The desire to find lasting solutions to epilepsy among humans increases every day.
Oyebamiji Abel Kolawole +10 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The study of kinetic models for ligand exchange of anions as ligands using ligand-exchange resin
Journal of Applied Polymer Science, 1997 A comparative study of kinetic models for ligand exchange of I− Cl− and Br− Cl− as ligands as a function of pH and concentration using diaminoethyl-sporopollenin (DAE-sporopollenin) resin were investigated during the ligand-exchange reaction of the liquid phase.
Ersoz, M, Yigitoglu, M, Ayar, A
openaire +3 more sources
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Synthesis and Characterisation of Cycloaurated Gold(III) Complexes with Bidentate (O,O), (N,S) and (S,S) Chelating Ligands [PDF]
, 2012 The reaction of C,N-coordinated gold(III) dihalides; BpAuCl₂ (Bp = 2 benzylpyridyl), AnpAuCl₂ (Anp = 2 anilinopyridyl) and TypAuCl₂ (Typ = 2 tolylpyridyl) with catecholate ligands in hot methanol and trimethylamine produced metallacycles with structural ...
Smith, Tiffany Sharee
core
Rational, computer-aided design of multi-target ligands : poster presentation from 6th German Conference on Chemoinformatics, GCC 2010, Goslar, Germany. 7-9 November 2010 [PDF]
, 2011 Over the past two decades the “one drug – one target – one disease” concept became the prevalent paradigm in drug discovery. The main idea of this approach is the identification of a single protein target whose inhibition leads to a successful treatment ...
Achenbach, Janosch +3 more
core +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Sigma receptor ligands: novel applications in cancer imaging and treatment [PDF]
, 2012 Sigma receptoren (subtypes sigma-1 en sigma-2) zijn unieke bindingsplaatsen die een aanzienlijk hogere expressie vertonen in kanker dan in gezond weefsel.
Rybczynska, Anna A., +1 more
core
Higher Denticity Ligands [PDF]
, 2003 Since the first edition of Comprehensive Coordination Chemistry (CCC, 1987) was published, the number of known multidentate ligands has increased dramatically.
A. Drozdov +5 more
core +1 more source