Results 241 to 250 of about 143,768 (336)

E3Docker: a docking server for potential E3 binder discovery. [PDF]

Nucleic Acids Res
Yan K, He W, Pang M, Lu X, Chen Z, Piao L, Zhang H, Wang Y, Chang S, Kong R.   +9 more
europepmc   +1 more source

The differential interactomes of the KRAS splice variants identify BIRC6 as a ubiquitin ligase for KRAS4A

Juan Andres Kochen Rossi, Cristina Nuevo‐Tapioles, Rachel A. O’Keefe, Moritz Hunkeler, Anna M. Schmoker, Mercedes Fissore-O'Leary, Wenjuan Su, Ian M. Ahearn, Cristina Branco, Hakyung Cheong, Dominic Esposito, Ioana Clotea, Beatrix Ueberheide, Eric S. Fischer, Mark R. Philips   +14 more
openalex   +1 more source

Roles of the TRAF6 and Pellino E3 ligases in MyD88 and RANKL signaling

Proceedings of the National Academy of Sciences of the United States of America, 2017
S. Strickson, Christoph H. Emmerich, E. T. Goh, Jiazhen Zhang, Ian R. Kelsall, Thomas J. Macartney, C. J. Hastie, A. Knebel, M. Peggie, F. Marchesi, J. Arthur, P. Cohen   +11 more
semanticscholar   +1 more source

HSP70 Interactome‐Mediated Proteolysis Targeting Chimera (HSP70‐PROTAC) for Ferroptosis‐Driven Cancer Treatment

Advanced Science, EarlyView.
This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong, Yulong Li, Hui Liang, Zumei Wu, Shiqun Wang, Yichao Wang, Jieyu Xu, Yanning Lan, Maohua Cai, Guangzhao Pan, Haiyan Yang, Kai Miao, Zhe‐Sheng Chen, Fangfang Tao, Xuelei Ma, Jiang‐Jiang Qin   +15 more
wiley   +1 more source

Genome-wide identification and functional analysis of U-box E3 ubiquitin ligases gene family related to drought stress response in Musa acuminata. [PDF]

BMC Plant Biol
Wei Y, Zhang F, Wang C, Ma M, Yang Y, Yuan Y, Dou T, Zhang S, Huang X.   +8 more
europepmc   +1 more source

The palmitoyl-CoA ligase Fum16 is part of a Fusarium verticillioides fumonisin subcluster involved in self-protection

Fabio Gherlone, Katarina Jojić, Ying Huang, Sandra Hoefgen, Vito Valiante, Slavica Janevska   +5 more
openalex   +1 more source

Hungry for Knowledge: Octopamine Signaling Regulates Hunger‐Enhanced Olfactory Learning

Advanced Science, EarlyView.
Researchers demonstrate that hunger state facilitates both aversive and appetitive olfactory learning. Two distinct octopamine signaling pathways are involved in aversive or appetitive memory formation in the hunger state. And, hunger state also facilitates the formation of both types of memories via an evolutionarily conserved norepinephrine (the ...
Huijuan Zhao, Guiyuan Shi, Ruixue Qin, Yinghao Sun, Wenbo Guo, Ruixia Shi, Minxian Peng, Jingxuan Yang, Jianjian Zhao, Qiuhan Liu, Jun Xiao, Ke Zhang, Qiang Liu, Wenxing Yang, He Liu   +14 more
wiley   +1 more source

<i>MMRN1</i> as a Potential Oncogene in Gastric Cancer: Functional Evidence from In Vitro Studies and Computational Prediction of <i>NEDD4L</i>-Mediated Ubiquitination. [PDF]

Curr Issues Mol Biol
Cai Z, Zhang M, Zeng Q, Deng Y, Li D.
europepmc   +1 more source

The Role of PIAS SUMO E3-Ligases in Cancer.

Cancer Research, 2017
A. Rabellino, C. Andreani, P. Scaglioni
semanticscholar   +1 more source